Reply to: Letter on the Effect of Fat Grafting on Scars Hyperpigmentation: A Systematic Review and Meta-Analysis
Our meta-analysis indicated favorable results in improving scar hyperpigmentation through fat grafting, but there remains a need for further investigation using objective measures to validate these clinical findings and elucidate the underlying mechanisms. Current evidence from animal studies showed...
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| Veröffentlicht in: | Aesthetic plastic surgery 2024-09, Vol.48 (17), p.3432-3433 |
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| container_title | Aesthetic plastic surgery |
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| creator | Alessandri Bonetti, Mario Arellano, Jose Antonio Egro, Francesco M. |
| description | Our meta-analysis indicated favorable results in improving scar hyperpigmentation through fat grafting, but there remains a need for further investigation using objective measures to validate these clinical findings and elucidate the underlying mechanisms. Current evidence from animal studies showed that fat grafting may exert its beneficial effects on scar hyperpigmentation through complex cellular and molecular pathways involving the regulation of melanin synthesis and skin remodeling. However, interpretation can be influenced by various factors, highlighting the importance of integrating multiple lines of evidence to draw robust conclusions.
Level of Evidence V
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors
www.springer.com/00266
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| doi_str_mv | 10.1007/s00266-024-04165-0 |
| format | Article |
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Level of Evidence V
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors
www.springer.com/00266
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Level of Evidence V
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors
www.springer.com/00266
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Level of Evidence V
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors
www.springer.com/00266
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| fulltext | fulltext |
| identifier | ISSN: 0364-216X |
| ispartof | Aesthetic plastic surgery, 2024-09, Vol.48 (17), p.3432-3433 |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adipose Tissue - transplantation Cicatrix - etiology Cicatrix - surgery Humans Hyperpigmentation - etiology Hyperpigmentation - surgery Medicine Medicine & Public Health Meta-Analysis as Topic Otorhinolaryngology Plastic Surgery Response to Letter to the Editor Systematic Reviews as Topic |
| title | Reply to: Letter on the Effect of Fat Grafting on Scars Hyperpigmentation: A Systematic Review and Meta-Analysis |
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