Nanoparticle-mediated celastrol ER targeting delivery amplify immunogenic cell death in melanoma

Endoplasmic reticulum (ER) stress is essential for activating intracellular signaling pathways of immunogenic cell death (ICD), targeting drugs to ER might improve ICDrelated immunotherapy. In this study, an ER targeting nanoparticle was designed to boost celastrol-induced cancer immunotherapy. The...

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Veröffentlicht in:	Journal of advanced research 2024-06
Hauptverfasser:	Wang, Fengling, Lai, Wenjing, Xie, Dandan, Zhou, Min, Wang, Jie, Xu, Rufu, Zhang, Rong, Li, Guobing
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemoimmunotherapy Endoplasmic reticulum (ER) stress Endoplasmic reticulum targeting Immunogenic cell death
Online-Zugang:	Volltext
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