Prussian Blue‐Derived Nanocomposite Synergized with Calcium Overload for Three‐Mode ROS Outbreak Generation to Enhance Oncotherapy

Calcium overload can lead to tumor cell death. However, because of the powerful calcium channel excretory system within tumor cells, simplistic calcium overloads do not allow for an effective antitumor therapy. Hence, the nanoparticles are created with polyethylene glycol (PEG) donor‐modified calciu...

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Veröffentlicht in:	Advanced healthcare materials 2024-09, Vol.13 (22), p.e2400591-n/a
Hauptverfasser:	Xu, Wenting, Zhou, Hongmei, Hu, Bangli, Liang, Xinqiang, Tang, Yanping, Ning, Shufang, Ding, He, Yang, Piaoping, Wang, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor activity Apoptosis Calcium (intracellular) Calcium channels Calcium efflux Calcium ions calcium overload Calcium phosphates Cell death Cytotoxicity Effectiveness Efflux Excretory system Glucose oxidase Glutathione glutathione depletion Heat generation Hypoxia Manganese Nanocomposites Nanoparticles Outbreaks Overloading photothermal effect Pigments Polyethylene glycol Prussian blue Reactive oxygen species ROS generation Therapy Tumor cells Tumors
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