Regulation of memory CD4+ T-cell generation by intrinsic and extrinsic IL-27 signaling during malaria infection

Abstract The generation and maintenance of memory T cells are regulated by various factors, including cytokines. Previous studies have shown that IL-27 is produced during the early acute phase of Plasmodium chabaudi chabaudi AS (Pcc) infection and inhibits the development of Th1-type memory CD4+ T c...

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Veröffentlicht in:	International immunology 2024-11, Vol.36 (12), p.629-640
Hauptverfasser:	Tsogtsaikhan, Sanjaadorj, Inoue, Shin-Ichi, Bayarsaikhan, Ganchimeg, Macalinao, Maria Lourdes, Kimura, Daisuke, Miyakoda, Mana, Yamamoto, Masahiro, Hara, Hiromitsu, Yoshida, Hiroki, Yui, Katsuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology Immunologic Memory - immunology Malaria - immunology Memory T Cells - immunology Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Plasmodium chabaudi - immunology Receptors, Interleukin - genetics Receptors, Interleukin - immunology Receptors, Interleukin - metabolism Signal Transduction - immunology
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