Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases

Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer’s disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS medicinal chemistry letters 2024-06, Vol.15 (6), p.750-751
Hauptverfasser: Sabnis, Ram W., Sabnis, Anika R.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 751
container_issue 6
container_start_page 750
container_title ACS medicinal chemistry letters
container_volume 15
creator Sabnis, Ram W.
Sabnis, Anika R.
description Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer’s disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds.
doi_str_mv 10.1021/acsmedchemlett.4c00178
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3070802721</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3070802721</sourcerecordid><originalsourceid>FETCH-LOGICAL-a349t-d4863d5461aeb428f9acb81be8129158beeb9cb98af73d213ea02d346fc448103</originalsourceid><addsrcrecordid>eNqFkM1OwzAQhC0EoqXwCpWPXFLs2EnsIyr_KgWJcrYce1NSJXGxk0q8PUENCE6cdrU7M6v9EJpSMqMkphfahBqseYO6gradcUMIzcQBGlPJRZSILDn81Y_QSQgbQlKZZeQYjZgQkkvKxuhh6XZQ4bmrt65rbMA64Bf6nOBHZ7tKt84HXDiPVx50WzZrvITOOwtraMD3kx3gqzKADhBO0VGhqwBnQ52g15vr1fwuWjzd3s8vF5FmXLaR5SJlNuEp1ZDzWBRSm1zQHASNJU1EDpBLk0uhi4zZmDLQJLaMp4XhXFDCJuh8n7v17r2D0Kq6DAaqSjfguqAYyYggcdZbJyjdS413IXgo1NaXtfYfihL1xVH95agGjr1xOtzo8n7_Y_sG1wvivaAPUBvX-aZ_-b_UTz9IhJM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3070802721</pqid></control><display><type>article</type><title>Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases</title><source>ACS Publications</source><creator>Sabnis, Ram W. ; Sabnis, Anika R.</creator><creatorcontrib>Sabnis, Ram W. ; Sabnis, Anika R.</creatorcontrib><description>Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer’s disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds.</description><identifier>ISSN: 1948-5875</identifier><identifier>EISSN: 1948-5875</identifier><identifier>DOI: 10.1021/acsmedchemlett.4c00178</identifier><identifier>PMID: 38894913</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><ispartof>ACS medicinal chemistry letters, 2024-06, Vol.15 (6), p.750-751</ispartof><rights>Published 2024 by American Chemical Society</rights><rights>Published 2024 by American Chemical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-a349t-d4863d5461aeb428f9acb81be8129158beeb9cb98af73d213ea02d346fc448103</cites><orcidid>0009-0008-9940-6583</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00178$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acsmedchemlett.4c00178$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,778,782,2754,27059,27907,27908,56721,56771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38894913$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sabnis, Ram W.</creatorcontrib><creatorcontrib>Sabnis, Anika R.</creatorcontrib><title>Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases</title><title>ACS medicinal chemistry letters</title><addtitle>ACS Med. Chem. Lett</addtitle><description>Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer’s disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds.</description><issn>1948-5875</issn><issn>1948-5875</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFkM1OwzAQhC0EoqXwCpWPXFLs2EnsIyr_KgWJcrYce1NSJXGxk0q8PUENCE6cdrU7M6v9EJpSMqMkphfahBqseYO6gradcUMIzcQBGlPJRZSILDn81Y_QSQgbQlKZZeQYjZgQkkvKxuhh6XZQ4bmrt65rbMA64Bf6nOBHZ7tKt84HXDiPVx50WzZrvITOOwtraMD3kx3gqzKADhBO0VGhqwBnQ52g15vr1fwuWjzd3s8vF5FmXLaR5SJlNuEp1ZDzWBRSm1zQHASNJU1EDpBLk0uhi4zZmDLQJLaMp4XhXFDCJuh8n7v17r2D0Kq6DAaqSjfguqAYyYggcdZbJyjdS413IXgo1NaXtfYfihL1xVH95agGjr1xOtzo8n7_Y_sG1wvivaAPUBvX-aZ_-b_UTz9IhJM</recordid><startdate>20240613</startdate><enddate>20240613</enddate><creator>Sabnis, Ram W.</creator><creator>Sabnis, Anika R.</creator><general>American Chemical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0008-9940-6583</orcidid></search><sort><creationdate>20240613</creationdate><title>Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases</title><author>Sabnis, Ram W. ; Sabnis, Anika R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a349t-d4863d5461aeb428f9acb81be8129158beeb9cb98af73d213ea02d346fc448103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sabnis, Ram W.</creatorcontrib><creatorcontrib>Sabnis, Anika R.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ACS medicinal chemistry letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sabnis, Ram W.</au><au>Sabnis, Anika R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases</atitle><jtitle>ACS medicinal chemistry letters</jtitle><addtitle>ACS Med. Chem. Lett</addtitle><date>2024-06-13</date><risdate>2024</risdate><volume>15</volume><issue>6</issue><spage>750</spage><epage>751</epage><pages>750-751</pages><issn>1948-5875</issn><eissn>1948-5875</eissn><abstract>Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer’s disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>38894913</pmid><doi>10.1021/acsmedchemlett.4c00178</doi><tpages>2</tpages><orcidid>https://orcid.org/0009-0008-9940-6583</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1948-5875
ispartof ACS medicinal chemistry letters, 2024-06, Vol.15 (6), p.750-751
issn 1948-5875
1948-5875
language eng
recordid cdi_proquest_miscellaneous_3070802721
source ACS Publications
title Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T08%3A37%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Novel%20Compounds%20as%20S1P5%20Modulators%20for%20Treating%20Neurodegenerative%20Diseases&rft.jtitle=ACS%20medicinal%20chemistry%20letters&rft.au=Sabnis,%20Ram%20W.&rft.date=2024-06-13&rft.volume=15&rft.issue=6&rft.spage=750&rft.epage=751&rft.pages=750-751&rft.issn=1948-5875&rft.eissn=1948-5875&rft_id=info:doi/10.1021/acsmedchemlett.4c00178&rft_dat=%3Cproquest_cross%3E3070802721%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3070802721&rft_id=info:pmid/38894913&rfr_iscdi=true