Platelet Membrane‐Coated Curcumin‐PLGA Nanoparticles Promote Astrocyte‐Neuron Transdifferentiation for Intracerebral Hemorrhage Treatment

Intracerebral hemorrhage (ICH) is a hemorrhagic disease with high mortality and disability rates. Curcumin is a promising drug for ICH treatment due to its multiple biological activities, but its application is limited by its poor watersolubility and instability. Herein, platelet membrane‐coated cur...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2024-10, Vol.20 (42), p.e2311128-n/a
Hauptverfasser:	Xu, Ximing, Zhang, Xinyu, Li, Ran, Yang, Xiufen, Fu, Peng, Feng, Ruijie, Sun, Xuan, Wang, Zhe, Yu, Jiangnan, Cao, Xia, Yu, Qingtong, Wang, Qilong, Liu, Sitong, Yang, Xiaoxia, Zhu, Yuan, Shi, Wentao, Deng, Wenwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocytes Astrocytes - drug effects Blood Platelets - drug effects cell membrane Cell Membrane - drug effects Cell Membrane - metabolism Cell membranes Cell Proliferation - drug effects Cell Transdifferentiation - drug effects Cerebral Hemorrhage - drug therapy Cerebral Hemorrhage - pathology Composite materials curcumin Curcumin - chemistry Curcumin - pharmacology Effectiveness Fourier transforms Glycolic acid Hemorrhage hemorrhagic injuries Infrared spectra Male Nanoparticles Nanoparticles - chemistry neuronal transdifferentiation Neurons - cytology Neurons - drug effects Platelets Polylactic Acid-Polyglycolic Acid Copolymer - chemistry Rats Rats, Sprague-Dawley Stroke Sustained release
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