SLIVER: Unveiling large scale gene regulatory networks of single-cell transcriptomic data through causal structure learning and modules aggregation

Prevalent Gene Regulatory Network (GRN) construction methods rely on generalized correlation analysis. However, in biological systems, regulation is essentially a causal relationship that cannot be adequately captured solely through correlation. Therefore, it is more reasonable to infer GRNs from a...

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Veröffentlicht in:Computers in biology and medicine 2024-08, Vol.178, p.108690, Article 108690
Hauptverfasser: Jiang, Hongyang, Wang, Yuezhu, Yin, Chaoyi, Pan, Hao, Chen, Liqun, Feng, Ke, Chang, Yi, Sun, Huiyan
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Sprache:eng
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