Is Cention-N comparable to other direct dental restorative materials? A systematic review with network meta-analysis of in vitro studies
To compare the performance of Cention-N® with direct restorative materials used at the daily practice (e.g., resin-based composites/RBC, glass ionomer cements/GIC, bioactive resins, silver amalgam) via a systematic review study. The review followed the PRISMA-NMA recommendations, and the protocol of...
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| Veröffentlicht in: | Dental materials 2024-09, Vol.40 (9), p.1341-1352 |
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| creator | Justen, Michelli Scheck, Débora Münchow, Eliseu Aldrighi Jardim, Juliana Jobim |
| description | To compare the performance of Cention-N® with direct restorative materials used at the daily practice (e.g., resin-based composites/RBC, glass ionomer cements/GIC, bioactive resins, silver amalgam) via a systematic review study.
The review followed the PRISMA-NMA recommendations, and the protocol of the review was published at osf.io/ybde8. The search was conducted in PubMed/MEDLINE, Scopus, Web of Science, Embase, Lilacs, and SciELO databases, as well as in the grey literature (Open Grey, Proquest, and Periódicos CAPES). Studies with an in vitro experimental design evaluating the characteristics and properties of Cention-N in comparison to other restorative materials were included. The risk of bias of included studies was assessed using the RoBDEMAT tool, and meta-analyses were conducted using Review Manager 5.4 and MetaInsight V3 tools.
A total of 85 studies were included in the review, from which 79 were meta-analyzed. Several characteristics of direct restorative materials were analyzed, including physical (color change, degree of conversion, hardness, microleakage, polymerization rate, roughness, water solubility, water sorption), mechanical (bond strength to dentin, compressive strength, diametral tensile strength, flexural modulus, flexural strength, load-to-fracture, wear), and biological (alkalinizing effect, antibacterial activity, calcium and fluoride release) properties.
Cention-N presented similar physico-mechanical properties compared to RBCs, but a stronger behavior than GICs. Despite the Alkasite nature of Cention-N, GICs may still demonstrate the greatest fluoride releasing ability from all direct restorative materials. This review confirmed the adequate behavior of Cention-N when compared to several other more traditionally used materials, confirming its applicability for the permanent restoration of decayed or fractured teeth.
•Systematic review with meta-analysis that evaluates the physical-mechanical and biological properties of Cention-N.•Cention-N has superior properties to glass ionomer cement in terms of several properties.•Limitations of Cention-N are limited to color variety and manual manipulation. |
| doi_str_mv | 10.1016/j.dental.2024.06.014 |
| format | Article |
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The review followed the PRISMA-NMA recommendations, and the protocol of the review was published at osf.io/ybde8. The search was conducted in PubMed/MEDLINE, Scopus, Web of Science, Embase, Lilacs, and SciELO databases, as well as in the grey literature (Open Grey, Proquest, and Periódicos CAPES). Studies with an in vitro experimental design evaluating the characteristics and properties of Cention-N in comparison to other restorative materials were included. The risk of bias of included studies was assessed using the RoBDEMAT tool, and meta-analyses were conducted using Review Manager 5.4 and MetaInsight V3 tools.
A total of 85 studies were included in the review, from which 79 were meta-analyzed. Several characteristics of direct restorative materials were analyzed, including physical (color change, degree of conversion, hardness, microleakage, polymerization rate, roughness, water solubility, water sorption), mechanical (bond strength to dentin, compressive strength, diametral tensile strength, flexural modulus, flexural strength, load-to-fracture, wear), and biological (alkalinizing effect, antibacterial activity, calcium and fluoride release) properties.
Cention-N presented similar physico-mechanical properties compared to RBCs, but a stronger behavior than GICs. Despite the Alkasite nature of Cention-N, GICs may still demonstrate the greatest fluoride releasing ability from all direct restorative materials. This review confirmed the adequate behavior of Cention-N when compared to several other more traditionally used materials, confirming its applicability for the permanent restoration of decayed or fractured teeth.
•Systematic review with meta-analysis that evaluates the physical-mechanical and biological properties of Cention-N.•Cention-N has superior properties to glass ionomer cement in terms of several properties.•Limitations of Cention-N are limited to color variety and manual manipulation.</description><identifier>ISSN: 0109-5641</identifier><identifier>ISSN: 1879-0097</identifier><identifier>EISSN: 1879-0097</identifier><identifier>DOI: 10.1016/j.dental.2024.06.014</identifier><identifier>PMID: 38880724</identifier><language>eng</language><publisher>England: Elsevier Inc</publisher><subject>Alkasite ; Biological properties ; Cention-N ; Composite Resins - chemistry ; Dental materials ; Dental Materials - chemistry ; Dental Restoration, Permanent ; Flexural Strength ; Glass Ionomer Cements - chemistry ; Humans ; In Vitro Techniques ; Materials Testing ; Mechanical properties ; Network Meta-Analysis ; Physical properties ; Systematic review</subject><ispartof>Dental materials, 2024-09, Vol.40 (9), p.1341-1352</ispartof><rights>2024 Elsevier Inc.</rights><rights>Copyright © 2024 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c311t-6d1a9c7391fd982c914900ec9e40c6f48f0285e538c6ec1017287f17adf513ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0109564124001556$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38880724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Justen, Michelli</creatorcontrib><creatorcontrib>Scheck, Débora</creatorcontrib><creatorcontrib>Münchow, Eliseu Aldrighi</creatorcontrib><creatorcontrib>Jardim, Juliana Jobim</creatorcontrib><title>Is Cention-N comparable to other direct dental restorative materials? A systematic review with network meta-analysis of in vitro studies</title><title>Dental materials</title><addtitle>Dent Mater</addtitle><description>To compare the performance of Cention-N® with direct restorative materials used at the daily practice (e.g., resin-based composites/RBC, glass ionomer cements/GIC, bioactive resins, silver amalgam) via a systematic review study.
The review followed the PRISMA-NMA recommendations, and the protocol of the review was published at osf.io/ybde8. The search was conducted in PubMed/MEDLINE, Scopus, Web of Science, Embase, Lilacs, and SciELO databases, as well as in the grey literature (Open Grey, Proquest, and Periódicos CAPES). Studies with an in vitro experimental design evaluating the characteristics and properties of Cention-N in comparison to other restorative materials were included. The risk of bias of included studies was assessed using the RoBDEMAT tool, and meta-analyses were conducted using Review Manager 5.4 and MetaInsight V3 tools.
A total of 85 studies were included in the review, from which 79 were meta-analyzed. Several characteristics of direct restorative materials were analyzed, including physical (color change, degree of conversion, hardness, microleakage, polymerization rate, roughness, water solubility, water sorption), mechanical (bond strength to dentin, compressive strength, diametral tensile strength, flexural modulus, flexural strength, load-to-fracture, wear), and biological (alkalinizing effect, antibacterial activity, calcium and fluoride release) properties.
Cention-N presented similar physico-mechanical properties compared to RBCs, but a stronger behavior than GICs. Despite the Alkasite nature of Cention-N, GICs may still demonstrate the greatest fluoride releasing ability from all direct restorative materials. This review confirmed the adequate behavior of Cention-N when compared to several other more traditionally used materials, confirming its applicability for the permanent restoration of decayed or fractured teeth.
•Systematic review with meta-analysis that evaluates the physical-mechanical and biological properties of Cention-N.•Cention-N has superior properties to glass ionomer cement in terms of several properties.•Limitations of Cention-N are limited to color variety and manual manipulation.</description><subject>Alkasite</subject><subject>Biological properties</subject><subject>Cention-N</subject><subject>Composite Resins - chemistry</subject><subject>Dental materials</subject><subject>Dental Materials - chemistry</subject><subject>Dental Restoration, Permanent</subject><subject>Flexural Strength</subject><subject>Glass Ionomer Cements - chemistry</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Materials Testing</subject><subject>Mechanical properties</subject><subject>Network Meta-Analysis</subject><subject>Physical properties</subject><subject>Systematic review</subject><issn>0109-5641</issn><issn>1879-0097</issn><issn>1879-0097</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFP3DAQha2qVVlo_wFCPvaSMJN4E_tChVZtQULlAmfLOBPhJYkX27ur_Qf92RgFeuQ00uib9zTvMXaKUCJgc74uO5qSGcoKKlFCUwKKT2yBslUFgGo_swUgqGLZCDxixzGuAUBUCr-yo1pKCW0lFuzfdeSrrOP8VPzl1o8bE8zDQDx57tMjBd65QDbx2YwHiskHk9yO-GgSBWeG-JNf8niIifLG2czsHO353qVHPlHa-_DER0qmMJMZDtFF7nvuJr5zKXge07ZzFL-xL32Wou9v84Td__51t7oqbm7_XK8ubwpbI6ai6dAo29YK-07JyioUCoCsIgG26YXsoZJLWtbSNmRzUG0l2x5b0_VLrMnWJ-zHrLsJ_nmbv9Gji5aGwUzkt1HX0ChsUUnMqJhRG3yMgXq9CW404aAR9GsHeq3nWPRrBxoanTvIZ2dvDtuHkbr_R--hZ-BiBij_maMKOlpHk6U5at1597HDCxllnBs</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Justen, Michelli</creator><creator>Scheck, Débora</creator><creator>Münchow, Eliseu Aldrighi</creator><creator>Jardim, Juliana Jobim</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20240901</creationdate><title>Is Cention-N comparable to other direct dental restorative materials? A systematic review with network meta-analysis of in vitro studies</title><author>Justen, Michelli ; Scheck, Débora ; Münchow, Eliseu Aldrighi ; Jardim, Juliana Jobim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c311t-6d1a9c7391fd982c914900ec9e40c6f48f0285e538c6ec1017287f17adf513ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Alkasite</topic><topic>Biological properties</topic><topic>Cention-N</topic><topic>Composite Resins - chemistry</topic><topic>Dental materials</topic><topic>Dental Materials - chemistry</topic><topic>Dental Restoration, Permanent</topic><topic>Flexural Strength</topic><topic>Glass Ionomer Cements - chemistry</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Materials Testing</topic><topic>Mechanical properties</topic><topic>Network Meta-Analysis</topic><topic>Physical properties</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Justen, Michelli</creatorcontrib><creatorcontrib>Scheck, Débora</creatorcontrib><creatorcontrib>Münchow, Eliseu Aldrighi</creatorcontrib><creatorcontrib>Jardim, Juliana Jobim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dental materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Justen, Michelli</au><au>Scheck, Débora</au><au>Münchow, Eliseu Aldrighi</au><au>Jardim, Juliana Jobim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is Cention-N comparable to other direct dental restorative materials? A systematic review with network meta-analysis of in vitro studies</atitle><jtitle>Dental materials</jtitle><addtitle>Dent Mater</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>40</volume><issue>9</issue><spage>1341</spage><epage>1352</epage><pages>1341-1352</pages><issn>0109-5641</issn><issn>1879-0097</issn><eissn>1879-0097</eissn><abstract>To compare the performance of Cention-N® with direct restorative materials used at the daily practice (e.g., resin-based composites/RBC, glass ionomer cements/GIC, bioactive resins, silver amalgam) via a systematic review study.
The review followed the PRISMA-NMA recommendations, and the protocol of the review was published at osf.io/ybde8. The search was conducted in PubMed/MEDLINE, Scopus, Web of Science, Embase, Lilacs, and SciELO databases, as well as in the grey literature (Open Grey, Proquest, and Periódicos CAPES). Studies with an in vitro experimental design evaluating the characteristics and properties of Cention-N in comparison to other restorative materials were included. The risk of bias of included studies was assessed using the RoBDEMAT tool, and meta-analyses were conducted using Review Manager 5.4 and MetaInsight V3 tools.
A total of 85 studies were included in the review, from which 79 were meta-analyzed. Several characteristics of direct restorative materials were analyzed, including physical (color change, degree of conversion, hardness, microleakage, polymerization rate, roughness, water solubility, water sorption), mechanical (bond strength to dentin, compressive strength, diametral tensile strength, flexural modulus, flexural strength, load-to-fracture, wear), and biological (alkalinizing effect, antibacterial activity, calcium and fluoride release) properties.
Cention-N presented similar physico-mechanical properties compared to RBCs, but a stronger behavior than GICs. Despite the Alkasite nature of Cention-N, GICs may still demonstrate the greatest fluoride releasing ability from all direct restorative materials. This review confirmed the adequate behavior of Cention-N when compared to several other more traditionally used materials, confirming its applicability for the permanent restoration of decayed or fractured teeth.
•Systematic review with meta-analysis that evaluates the physical-mechanical and biological properties of Cention-N.•Cention-N has superior properties to glass ionomer cement in terms of several properties.•Limitations of Cention-N are limited to color variety and manual manipulation.</abstract><cop>England</cop><pub>Elsevier Inc</pub><pmid>38880724</pmid><doi>10.1016/j.dental.2024.06.014</doi><tpages>12</tpages></addata></record> |
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| ispartof | Dental materials, 2024-09, Vol.40 (9), p.1341-1352 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Alkasite Biological properties Cention-N Composite Resins - chemistry Dental materials Dental Materials - chemistry Dental Restoration, Permanent Flexural Strength Glass Ionomer Cements - chemistry Humans In Vitro Techniques Materials Testing Mechanical properties Network Meta-Analysis Physical properties Systematic review |
| title | Is Cention-N comparable to other direct dental restorative materials? A systematic review with network meta-analysis of in vitro studies |
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