Rational Design of Drugs Targeting G-Protein-Coupled Receptors: Ligand Search and Screening

G protein-coupled receptors (GPCRs) are transmembrane proteins that participate in many physiological processes and represent major pharmacological targets. Recent advances in structural biology of GPCRs have enabled the development of drugs based on the receptor structure (structure-based drug desi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Moscow) 2024-05, Vol.89 (5), p.958-972
Hauptverfasser:	Luginina, Aleksandra P., Khnykin, Andrey. N., Khorn, Polina A., Moiseeva, Olga V., Safronova, Nadezhda A., Pospelov, Vladimir A., Dashevskii, Dmitrii E., Belousov, Anatolii S., Borschevskiy, Valentin I., Mishin, Alexey V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Bioinformatics Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Computational chemistry Drug delivery Drug Design Drug development Drugs Functional testing G protein-coupled receptors Humans Information processing Life Sciences Ligands Microbiology Protein structure Proteins R&D Receptors Receptors, G-Protein-Coupled - chemistry Receptors, G-Protein-Coupled - metabolism Research & development Review Screening
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!