Effect of maternal cigarette smoke exposure on COPD progression in offspring mice

To investigate the impact of maternal smoking on chronic obstructive pulmonary disease (COPD) progression in offspring. Using female C57BL/6 J mice, a maternal cigarette smoke exposure (CSE) model was established. Mice were exposed to cigarette smoke for 2 hours/day, 7 days/week, with a minimum 4-ho...

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Veröffentlicht in:	Reproductive toxicology (Elmsford, N.Y.) N.Y.), 2024-09, Vol.128, p.108646, Article 108646
Hauptverfasser:	Sun, Jiawei, Chen, Huan, Xu, Xu, Dou, Yaping, Wu, Baofa, Zhang, Hongyang, Shang, Song, Sun, Wuzhuang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Cell apoptosis Cigarette smoke exposure COPD Disease Progression Female Lung - drug effects Lung - pathology Lung - ultrastructure Male Maternal Exposure - adverse effects Mice Mice, Inbred C57BL Mitochondria - drug effects Mitochondria - ultrastructure Mitochondrial dysfunction Pregnancy Prenatal Exposure Delayed Effects Pulmonary Disease, Chronic Obstructive - chemically induced Pulmonary Disease, Chronic Obstructive - etiology Pulmonary Disease, Chronic Obstructive - pathology Smoke - adverse effects VDAC-1
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