Exosome-loaded hyaluronic acid hydrogel composite with oxygen-producing 3D printed polylactic acid scaffolds for bone tissue repair and regeneration

Bone defects can interfere with bone healing by disrupting the local environment, resulting in vascular damage and hypoxia. Under these conditions, insufficient oxygen availability is a significant factor that exacerbates disease by blocking angiogenesis or osteogenesis. Exosomes play a crucial role...

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Veröffentlicht in:International journal of biological macromolecules 2024-08, Vol.274 (Pt 1), p.132970, Article 132970
Hauptverfasser: Zhang, Yifan, Fang, Min, Zhu, Junbin, Li, Ting, Li, Na, Su, Bo, Sun, Guo-Dong, Li, Lihua, Zhou, Changren
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Sprache:eng
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