Consolidation with First and Second Allogeneic Transplants in Adults with Relapsed/Refractory B-ALL Following Response to CD19CAR T Cell Therapy

•AlloHCT post CAR-T response is feasible and associated with low early NRM.•AlloHCT outcomes in CAR-T responders were encouraging in high-risk r/r B-ALL.•Encouraging outcomes extend to CAR-T responders undergoing second transplant. CD19-targeted chimeric antigen receptor T cell (CAR-T) therapy has l...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Transplantation and cellular therapy 2024-08, Vol.30 (8), p.788.e1-788.e9
Hauptverfasser:	Aldoss, Ibrahim, Shan, Haoyue, Yang, Dongyun, Clark, Mary C., Al Malki, Monzr, Aribi, Ahmed, Agrawal, Vaibhav, Sandhu, Karamjeet, Salhotra, Amandeep, Pourhassan, Hoda, Koller, Paul, Ali, Haris, Artz, Andrew, Karras, Nicole, Pawlowska, Anna B., Murphy, Lindsey, Palmer, Joycelynne, Stein, Anthony, Marcucci, Guido, Pullarkat, Vinod, Nakamura, Ryotaro, Forman, Stephen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Allogeneic hematopoietic cell transplantation CD19 CAR T cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!