BCAT1 alleviates early brain injury by inhibiting ferroptosis through PI3K/AKT/mTOR/GPX4 pathway after subarachnoid hemorrhage

Regulation of the redox system by branched-chain amino acid transferase 1 (BCAT1) is of great significance in the occurrence and development of diseases, but the relationship between BCAT1 and subarachnoid hemorrhage (SAH) is still unknown. Ferroptosis, featured by iron-dependent lipid peroxidation...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Free radical biology & medicine 2024-09, Vol.222, p.173-186
Hauptverfasser:	Liu, Nan, Li, Chen, Yan, Cong, Yan, Hao-chen, Jin, Bing-xuan, Yang, Hong-rui, Jiang, Guang-you, Gong, Hai-dong, Li, Ji-yi, Ma, Sheng-ji, Liu, Huai-lei, Gao, Cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	BCAT1 Early brain injury Ferroptosis GPX4 Lipid peroxidation Subarachnoid hemorrhage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!