Identification and structural elucidation of an oxidation product generated during stability studies of Cabergoline drug product

Cabergoline is a dopamine agonist with applications as anti-Parkinson drug and prolactin inhibitor. The cabergoline drug product Laktostop® 50 µg/mL is used in veterinary medicine for lactation suppression in cats and dogs e.g. during false pregnancy. Recently, during ongoing HPLC stability testing...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2024-09, Vol.248, p.116282, Article 116282
Hauptverfasser:	Lechel, Tilman, Silva Otero, Ruben, Springer, Andreas, Rutkowski, Anja, Matzkow, Dominik, Zart, Johannes, Hartmann, Tobias, Hochhuth, Dieter
Format:	Artikel
Sprache:	eng
Schlagworte:	Cabergoline Cabergoline N-oxide Drug impurity Oxidation Structure evaluation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!