RGC-32 mediates proinflammatory and profibrotic pathways in immune-mediated kidney disease

Systemic lupus erythematosus is an autoimmune disease that results in immune-mediated damage to kidneys and other organs. We investigated the role of response gene to complement-32 (RGC-32), a proinflammatory and profibrotic mediator induced by TGFβ and C5b-9, in nephrotoxic nephritis (NTN), an expe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2024-08, Vol.265, p.110279, Article 110279
Hauptverfasser:	Tatomir, Alexandru, Vlaicu, Sonia, Nguyen, Vinh, Luzina, Irina G., Atamas, Sergei P., Drachenberg, Cinthia, Papadimitriou, John, Badea, Tudor C., Rus, Horea G., Rus, Violeta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmunity Disease Models, Animal Fibrosis Humans Inflammation - immunology Kidney - immunology Kidney - pathology Lupus Nephritis - immunology Lupus Nephritis - pathology Mice Mice, Inbred C57BL Mice, Knockout Nephrotoxic nephritis Nuclear Proteins Response gene to complement-32 Th1 Cells - immunology Th17 Cells - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!