Sensitivity to antimicrobial peptide A (SapA) contributes to the survival of Salmonella typhimurium against antimicrobial peptides, neutrophils and virulence in mice

Host-generated antimicrobial peptides (AMPs) play a pivotal role in defense against bacterial pathogens. AMPs kill invading bacteria majorly by disrupting the bacterial cell walls. AMPs are actively synthesized and released into the lumen of the gastrointestinal tract to limit colonization of enteri...

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Veröffentlicht in:	Archives of microbiology 2024-07, Vol.206 (7), p.302, Article 302
Hauptverfasser:	Nagappan, Sabapathi, Apoorva, Shekhar, Shome, Arijit, Bishnoi, Shikha, Shrivastava, Sameer, Mahawar, Manish
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Cationic Peptides - pharmacology Antimicrobial peptides Antimicrobial Peptides - pharmacology Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Biochemistry Biomedical and Life Sciences Biotechnology Cell Biology Cell walls Ecology Female Gastrointestinal system Gastrointestinal tract Hypersensitivity Leukocytes (neutrophilic) Life Sciences Mastoparan Mice Mice, Inbred BALB C Microbial Ecology Microbiology Mutants Neutrophils Neutrophils - immunology Neutrophils - microbiology Original Paper Pathogens Peptides Salmonella Salmonella Infections - microbiology Salmonella typhimurium - drug effects Salmonella typhimurium - genetics Salmonella typhimurium - pathogenicity Survival Virulence
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