DNA Anchoring Strength Directly Correlates with Spherical Nucleic Acid–Based HPV E7 Cancer Vaccine Potency

Vaccination for cancers arising from human papillomavirus (HPV) infection holds immense potential, yet clinical success has been elusive. Herein, we describe vaccination studies involving spherical nucleic acids (SNAs) incorporating a CpG adjuvant and a peptide antigen (E711–19) from the HPV-E7 onco...

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Veröffentlicht in:	Nano letters 2024-06, Vol.24 (25), p.7629-7636
Hauptverfasser:	Hwang, Jeongmin, Dittmar, Jasper Wilson, Kang, Janice, Ocampo, Tonatiuh, Evangelopoulos, Michael, Han, Zhenyu, Kudruk, Sergej, Lorch, Jochen, Mirkin, Chad A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Vaccines - administration & dosage Cancer Vaccines - chemistry Cancer Vaccines - immunology CD8-Positive T-Lymphocytes - immunology Cell Line, Tumor DNA - chemistry DNA - immunology Humans Mice Nucleic Acids - chemistry Nucleic Acids - immunology Papillomavirus E7 Proteins - chemistry Papillomavirus E7 Proteins - immunology Papillomavirus Infections - immunology Papillomavirus Infections - prevention & control
Online-Zugang:	Volltext
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