Adiponectin rescues synaptic plasticity in the dentate gyrus of a mouse model of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and is the leading known single-gene cause of autism spectrum disorder. Patients with FXS display varied behavioural deficits that include mild to severe cognitive impairments in addition to mood disorders. Curren...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2024-07, Vol.379 (1906), p.20230221
Hauptverfasser:	Thacker, Jonathan S, Bettio, Luis, Liang, Stanley, Shkolnikov, Irene, Collingridge, Graham L, Christie, Brian R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - metabolism Animals Dentate Gyrus - drug effects Dentate Gyrus - metabolism Disease Models, Animal Fragile X Mental Retardation Protein - genetics Fragile X Mental Retardation Protein - metabolism Fragile X Syndrome - drug therapy Fragile X Syndrome - metabolism Fragile X Syndrome - physiopathology Long-Term Potentiation - drug effects Male Mice Mice, Knockout Neuronal Plasticity - drug effects Receptors, AMPA - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!