Nanoparticle-hydrogel composite as dual-drug delivery system for the potential application of corneal graft rejection

[Display omitted] Immune rejection remains the major cause of corneal graft failure. Immunosuppressants (such as rapamycin; RAPA) adjunctive to antibiotics (such as levofloxacin hydrochloride; Lev) are a clinical mainstay after corneal grafts but suffer from poor ocular bioavailability associated wi...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2024-08, Vol.201, p.114351, Article 114351
Hauptverfasser:	Xu, Xiaoning, Wu, Yuqin, Gu, Ruiling, Zhang, Zhaoliang, Liu, Xiangyi, Hu, Yuhan, Li, Xingyi, Lin, Deqing, Bao, Zhishu
Format:	Artikel
Sprache:	eng
Schlagworte:	Corneal grafts Hydrogel Immunosuppressants Micelles Ocular bioavailability
Online-Zugang:	Volltext
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