MG53 binding to CAV3 facilitates activation of eNOS/NO signaling pathway to enhance the therapeutic benefits of bone marrow-derived mesenchymal stem cells in diabetic wound healing

•Our findings support the notion that MG53 binds to CAV3, activates eNOS/NO signaling pathway, and accelerates the therapeutic effect of BMSCs in the context of diabetic wound healing.•Besides, this study show that MG53 should accelerate the endothelial differentiation of BMSCs, and their transplant...

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Veröffentlicht in:	International immunopharmacology 2024-07, Vol.136, p.112410, Article 112410
Hauptverfasser:	Wu, Junwei, Feng, Yiyuan, Wang, Yan, He, Xiangfei, Chen, Zheyu, Lan, Dongyang, Wu, Xinchao, Wen, Jianguo, Tsung, Allan, Wang, Xinxin, Ma, Jianjie, Wu, Yudong
Format:	Artikel
Sprache:	eng
Schlagworte:	BMSCs CAV3 Diabetic wound healing eNOS/NO signaling MG53
Online-Zugang:	Volltext
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