Nickel‐Catalyzed Electrochemical Cross‐Electrophile C(sp2)−C(sp3) Coupling via a NiII Aryl Amido Intermediate

Cross‐electrophile coupling (XEC) between aryl halides and alkyl halides is a streamlined approach for C(sp2)−C(sp3) bond construction, which is highly valuable in medicinal chemistry. Based on a key NiII aryl amido intermediate, we developed a highly selective and scalable Ni‐catalyzed electrochemi...

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Veröffentlicht in:	Angewandte Chemie International Edition 2024-09, Vol.63 (38), p.e202407118-n/a
Hauptverfasser:	Luo, Jian, Davenport, Michael T., Ess, Daniel H., Liu, T. Leo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amido ligand Aromatic compounds Catalysts Chemical bonds Couplings Cross-electrophile coupling Electrochemistry Electrosynthesis Halides Ni catalysis Nickel Side reactions Substrates
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