Sideroflexin-1 promotes progression and sensitivity to lapatinib in triple-negative breast cancer by inhibiting TOLLIP-mediated autophagic degradation of CIP2A

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and it lacks specific therapeutic targets and effective treatment protocols. By analyzing a proteomic TNBC dataset, we found significant upregulation of sideroflexin 1 (SFXN1) in tumor tissues. However, the precise...

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Veröffentlicht in:	Cancer letters 2024-08, Vol.597, p.217008, Article 217008
Hauptverfasser:	Andriani, Lisa, Ling, Yun-Xiao, Yang, Shao-Ying, Zhao, Qian, Ma, Xiao-Yan, Huang, Min-Ying, Zhang, Yin-Ling, Zhang, Fang-Lin, Li, Da-Qiang, Shao, Zhi-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy CIP2A Lapatinib SFXN1 TNBC
Online-Zugang:	Volltext
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