Breast cancer after ovarian cancer in BRCA1 and BRCA2 pathogenic variant heterozygotes: Lower rates for 5 years post chemotherapy

The identification of germline BRCA1/BRCA2 pathogenic variants (PV) infer high remaining lifetime breast/ovarian cancer risks, but there is paucity of studies assessing breast cancer risk after ovarian cancer diagnosis. We reviewed the history of breast cancer in 895 PV heterozygotes (BRCA1 = 541)....

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Veröffentlicht in:	Genetics in medicine 2024-09, Vol.26 (9), p.101172, Article 101172
Hauptverfasser:	Evans, D. Gareth, Morgan, Robert D., Crosbie, Emma J., Howell, Sacha J., Forde, Claire, Howell, Anthony, Lalloo, Fiona, Woodward, Emma R.
Format:	Artikel
Sprache:	eng
Schlagworte:	BRCA1 BRCA2 Breast cancer Ovarian cancer Survival
Online-Zugang:	Volltext
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