Is genotoxicity a suitable biomarker for monitoring anabolic-androgenic steroids exposure in vivo? A systematic review and meta-analysis

Steroids stand for a class of hormones (natural and synthetic) known to be helpful for a number of disorders. Despite the aforementioned beneficial effects of using these hormones, anabolic-androgenic steroids (AAS) are also widely abused in a non-therapeutic manner for muscle-building and strength-...

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Veröffentlicht in:	Journal of applied toxicology 2025-01, Vol.45 (1), p.77-88
Hauptverfasser:	Pinto, Thiago Guedes, Malacarne, Ingra Tais, Takeshita, Wilton Mitsunari, de Barros Viana, Milena, Renno, Ana Claudia Muniz, Ribeiro, Daniel Araki
Format:	Artikel
Sprache:	eng
Schlagworte:	Anabolic Agents - toxicity Androgens - toxicity Animals Biomarkers Damage Data analysis Deoxyribonucleic acid DNA DNA damage DNA Damage - drug effects Exposure Genotoxicity Heterogeneity Hormones Humans In vivo methods and tests Male Meta-analysis Monitoring Mutagenicity Tests Rats Statistical analysis Steroid hormones Steroids Testis - drug effects Testis - metabolism Testis - pathology
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