Plasma soluble fms-like tyrosine kinase 1 to placental growth factor ratio of 11.5 multiples of median predicts preeclampsia with severe features within 2 weeks of testing

Angiogenic imbalances, characterized by an excess of antiangiogenic factors (soluble fms-like tyrosine kinase 1) and reduced angiogenic factors (vascular endothelial growth factor and placental growth factor), contribute to the mechanisms of disease in preeclampsia. The ratio of soluble fms-like tyr...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2024-09, Vol.231 (3), p.363.e1-363.e11
Hauptverfasser:	Espinoza, Jimmy, Calsavara, Vinicius F., Kilpatrick, Sarah, Rana, Sarosh, Costantine, Maged M., Boggess, Kim, Wylie, Blair J., Moore Simas, Tiffany A., Louis, Judette M., Gaw, Stephanie L., Murtha, Amy, Wiegand, Samantha, Gollin, Yvonne, Singh, Deepjot, Silver, Robert M., Durie, Danielle E., Panda, Britta, Norwitz, Errol R., Burd, Irina, Plunkett, Beth, Scott, Rachel K., Lemoine, Elizabeth, Thadhani, Ravi, Karumanchi, S. Ananth
Format:	Artikel
Sprache:	eng
Schlagworte:	11.5 adverse outcomes likelihood ratio MoM multiples of the median plasma prediction preeclampsia severe features sFlt-1/PlGF ratio
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