Group IVA Phospholipase A2 in Collagen-Producing Cells Promotes High-Fat Diet-Induced Infiltration of Inflammatory Cells into the Liver by Upregulating the Expression of MCP-1

Nonalcoholic steatohepatitis (NASH) is characterized by hepatic inflammation and fibrosis due to excessive fat accumulation. Monocyte chemoattractant protein-1 (MCP-1) is a key chemokine that infiltrates inflammatory cells into the liver during the development of NASH. Our previous studies demonstra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & pharmaceutical bulletin 2024/05/31, Vol.47(5), pp.1058-1065
Hauptverfasser:	Kishinaka, Saki, Kawashita, Eri, Nishizaki, Taichi, Ishihara, Keiichi, Akiba, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbon tetrachloride Chemokines Collagen Endothelial cells Fatty liver Fibrosis Gene expression group IVA phospholipase A2 hepatic inflammation hepatic stellate cell Hepatocytes High fat diet Infiltration Inflammation Liver Macrophages Monocyte chemoattractant protein Monocyte chemoattractant protein 1 Monocytes mRNA non-alcoholic steatohepatitis Phospholipase Phospholipase A2 Stellate cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!