Orbitostriatal encoding of reward delayed gratification and impulsivity in chronic pain

[Display omitted] •Chronic pain underlies central network malplasticity.•OFC-NAc dysfunctions may contribute to impairments in time-reward associations.•OFC-NAc role in the arising of cognitive deficits under chronic pain remains inconclusive.•This review explores recent advances on the topic to gui...

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Veröffentlicht in:	Brain research 2024-09, Vol.1839, p.149044, Article 149044
Hauptverfasser:	Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chronic Pain - physiopathology Chronic Pain - psychology Corpus Striatum - physiopathology Decision-making Delay Discounting - physiology Humans Impulsive Behavior - physiology Neural Pathways - physiopathology Nucleus accumbens Nucleus Accumbens - physiopathology Orbitofrontal cortex Orbitostriatal circuit Pain-related neuroplasticity Prefrontal Cortex - physiopathology Reward Reward valence
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