Heavy metals toxicity on epigenetic modifications in the pathogenesis of Alzheimer's disease (AD)

Alzheimer's disease (AD) is a progressive decline in cognitive ability and behavior which eventually disrupts daily activities. AD has no cure and the progression rate varies unlikely. Among various causative factors, heavy metals are reported to be a significant hazard in AD pathogenesis. Meta...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2024-06, Vol.38 (6), p.e23741-n/a
Hauptverfasser:	Venkatesan, Dhivya, Muthukumar, Sindduja, Iyer, Mahalaxmi, Babu, Harysh Winster Suresh, Gopalakrishnan, Abilash Valsala, Yadav, Mukesh Kumar, Vellingiri, Balachandar
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - chemically induced Alzheimer Disease - etiology Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer's disease Alzheimer's disease (AD) Amyloid beta-Peptides - metabolism Animals Arsenic Cadmium Cognitive ability Copper Epigenesis, Genetic - drug effects epigenetic modifications Epigenetics Heavy metals Humans Iron Lithium Metals, Heavy - toxicity Neurodegenerative diseases Neurological diseases neurotoxicity Pathogenesis Phosphorylation Reviews Tau protein tau Proteins - genetics tau Proteins - metabolism therapeutic approach Toxicity
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