Efficient inference of parent-of-origin effect using case-control mother–child genotype data

Parent-of-origin effect plays an important role in mammal development and disorder. Case-control mother–child pair genotype data can be used to detect parent-of-origin effect and is often convenient to collect in practice. Most existing methods for assessing parent-of-origin effect do not incorporat...

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Veröffentlicht in:	Journal of statistical planning and inference 2024-12, Vol.233, p.106190, Article 106190
Hauptverfasser:	Tian, Yuang, Zhang, Hong, Bureau, Alexandre, Hochner, Hagit, Chen, Jinbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Modified profile log-likelihood Mother–child pair Parent-of-origin effect
Online-Zugang:	Volltext
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