Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry
Aims Data on the prognostic impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim of this analysis was to evaluate 2‐year survival and symptomatic outcomes of patients in relation to residual TR after T‐TEER. Methods and result...
Gespeichert in:
| Veröffentlicht in: | European journal of heart failure 2024-08, Vol.26 (8), p.1850-1860 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1860 |
|---|---|
| container_issue | 8 |
| container_start_page | 1850 |
| container_title | European journal of heart failure |
| container_volume | 26 |
| creator | Stolz, Lukas Kresoja, Karl‐Patrik Stein, Jennifer Fortmeier, Vera Koell, Benedikt Rottbauer, Wolfgang Kassar, Mohammad Goebel, Bjoern Denti, Paolo Achouh, Paul Rassaf, Tienush Barreiro‐Perez, Manuel Boekstegers, Peter Rück, Andreas Doldi, Philipp M. Novotny, Julia Zdanyte, Monika Adamo, Marianna Vincent, Flavien Schlegel, Philipp Bardeleben, Ralph‐Stephan Stocker, Thomas J. Weckbach, Ludwig T. Wild, Mirjam G. Brunner, Stephanie Toggweiler, Stefan Grapsa, Julia Patterson, Tiffany Thiele, Holger Kister, Tobias Konstandin, Mathias H. Van Belle, Eric Metra, Marco Geisler, Tobias Estévez‐Loureiro, Rodrigo Luedike, Peter Karam, Nicole Maisano, Francesco Lauten, Philipp Praz, Fabien Kessler, Mirjam Kalbacher, Daniel Rudolph, Volker Iliadis, Christos Lurz, Philipp Hausleiter, Jörg Pfister, Roman Baldus, Stephan Gerçek, Muhammed Rudolph, Felix Ludwig, Sebastian Pauschinger, Christoph Schneider, Leonhard‐Moritz Felbel, Dominik Salomon, Carsten Lapp, Harald Puscas, Tania Berrebi, Alain Mahabadi, Amir Abbas Schindhelm, Florian Caneiro‐Queija, Berenice Echarte, Julio C Schreieck, Jürgen Goldschmied, Andreas Pancaldi, Edoardo Tomasoni, Daniela Rousse, Natacha Aghezzaf, Samy Frey, Norbert Kraus, Martin Rosch, Sebastian |
| description | Aims
Data on the prognostic impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim of this analysis was to evaluate 2‐year survival and symptomatic outcomes of patients in relation to residual TR after T‐TEER.
Methods and results
Using the large European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) we investigated the impact of residual TR on 2‐year all‐cause mortality and New York Heart Association (NYHA) functional class at follow‐up. The study further identified predictors for residual TR ≥3+ using a logistic regression model. The study included a total of 1286 T‐TEER patients (mean age 78.0 ± 8.9 years, 53.6% female). TR was successfully reduced to ≤1+ in 42.4%, 2+ in 40.0% and 3+ in 14.9% of patients at discharge, while 2.8% remained with TR ≥4+ after the procedure. Residual TR ≥3+ was an independent multivariable predictor of 2‐year all‐cause mortality (hazard ratio 2.06, 95% confidence interval 1.30–3.26, p = 0.002). The prevalence of residual TR ≥3+ was four times higher in patients with higher baseline TR (vena contracta >11.1 mm) and more severe tricuspid valve tenting (tenting area >1.92 cm2). Of note, no survival difference was observed in patients with residual TR ≤1+ versus 2+ (76.2% vs. 73.1%, p = 0.461). The rate of NYHA functional class ≥III at follow‐up was significantly higher in patients with residual TR ≥3+ (52.4% vs. 40.5%, p |
| doi_str_mv | 10.1002/ejhf.3274 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3062534447</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3062534447</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2904-c3ee5633659f2829ca4e4a701162a5a791936e3fffbcef6f26648b246c68b57c3</originalsourceid><addsrcrecordid>eNp1kEtOwzAQhi0EouWx4AIoS1iE-hUnYYeqloIqIaGyjhx33LpKk2I7Qt1xBM7ISXBoQWzYzIxmvvkWP0IXBN8QjOkAVkt9w2jKD1CfZGke44zzwzCzLIvzjNMeOnFuhTFJA36MemFPKM1pH22fwZl5K6vIW6NatzHzyMKitQvjpTdNHUntwf65eitrp6RfQreH-QI-3z98E0o3h-eNNPY2eqidWSy9i0ztmyjQ0ai1zey5sxvn7fYMHWlZOTjf91P0Mh7NhpN4-nT_MLybxormmMeKASSCMZHkmmY0V5IDlykmRFCZyDQnORPAtNalAi00FYJnJeVCiaxMUsVO0dXOu7HNawvOF2vjFFSVrKFpXcGwoAnjnKcBvd6hyjbOWdDFxpq1tNuC4KJLuuiSLrqkA3u517blGua_5E-0ARjsgDdTwfZ_UzF6nIy_lV8th4yo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3062534447</pqid></control><display><type>article</type><title>Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry</title><source>Wiley Online Library Journals Frontfile Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Stolz, Lukas ; Kresoja, Karl‐Patrik ; Stein, Jennifer ; Fortmeier, Vera ; Koell, Benedikt ; Rottbauer, Wolfgang ; Kassar, Mohammad ; Goebel, Bjoern ; Denti, Paolo ; Achouh, Paul ; Rassaf, Tienush ; Barreiro‐Perez, Manuel ; Boekstegers, Peter ; Rück, Andreas ; Doldi, Philipp M. ; Novotny, Julia ; Zdanyte, Monika ; Adamo, Marianna ; Vincent, Flavien ; Schlegel, Philipp ; Bardeleben, Ralph‐Stephan ; Stocker, Thomas J. ; Weckbach, Ludwig T. ; Wild, Mirjam G. ; Brunner, Stephanie ; Toggweiler, Stefan ; Grapsa, Julia ; Patterson, Tiffany ; Thiele, Holger ; Kister, Tobias ; Konstandin, Mathias H. ; Van Belle, Eric ; Metra, Marco ; Geisler, Tobias ; Estévez‐Loureiro, Rodrigo ; Luedike, Peter ; Karam, Nicole ; Maisano, Francesco ; Lauten, Philipp ; Praz, Fabien ; Kessler, Mirjam ; Kalbacher, Daniel ; Rudolph, Volker ; Iliadis, Christos ; Lurz, Philipp ; Hausleiter, Jörg ; Pfister, Roman ; Baldus, Stephan ; Gerçek, Muhammed ; Rudolph, Felix ; Ludwig, Sebastian ; Pauschinger, Christoph ; Schneider, Leonhard‐Moritz ; Felbel, Dominik ; Salomon, Carsten ; Lapp, Harald ; Puscas, Tania ; Berrebi, Alain ; Mahabadi, Amir Abbas ; Schindhelm, Florian ; Caneiro‐Queija, Berenice ; Echarte, Julio C ; Schreieck, Jürgen ; Goldschmied, Andreas ; Pancaldi, Edoardo ; Tomasoni, Daniela ; Rousse, Natacha ; Aghezzaf, Samy ; Frey, Norbert ; Kraus, Martin ; Rosch, Sebastian</creator><creatorcontrib>Stolz, Lukas ; Kresoja, Karl‐Patrik ; Stein, Jennifer ; Fortmeier, Vera ; Koell, Benedikt ; Rottbauer, Wolfgang ; Kassar, Mohammad ; Goebel, Bjoern ; Denti, Paolo ; Achouh, Paul ; Rassaf, Tienush ; Barreiro‐Perez, Manuel ; Boekstegers, Peter ; Rück, Andreas ; Doldi, Philipp M. ; Novotny, Julia ; Zdanyte, Monika ; Adamo, Marianna ; Vincent, Flavien ; Schlegel, Philipp ; Bardeleben, Ralph‐Stephan ; Stocker, Thomas J. ; Weckbach, Ludwig T. ; Wild, Mirjam G. ; Brunner, Stephanie ; Toggweiler, Stefan ; Grapsa, Julia ; Patterson, Tiffany ; Thiele, Holger ; Kister, Tobias ; Konstandin, Mathias H. ; Van Belle, Eric ; Metra, Marco ; Geisler, Tobias ; Estévez‐Loureiro, Rodrigo ; Luedike, Peter ; Karam, Nicole ; Maisano, Francesco ; Lauten, Philipp ; Praz, Fabien ; Kessler, Mirjam ; Kalbacher, Daniel ; Rudolph, Volker ; Iliadis, Christos ; Lurz, Philipp ; Hausleiter, Jörg ; Pfister, Roman ; Baldus, Stephan ; Gerçek, Muhammed ; Rudolph, Felix ; Ludwig, Sebastian ; Pauschinger, Christoph ; Schneider, Leonhard‐Moritz ; Felbel, Dominik ; Salomon, Carsten ; Lapp, Harald ; Puscas, Tania ; Berrebi, Alain ; Mahabadi, Amir Abbas ; Schindhelm, Florian ; Caneiro‐Queija, Berenice ; Echarte, Julio C ; Schreieck, Jürgen ; Goldschmied, Andreas ; Pancaldi, Edoardo ; Tomasoni, Daniela ; Rousse, Natacha ; Aghezzaf, Samy ; Frey, Norbert ; Kraus, Martin ; Rosch, Sebastian ; on behalf of the EuroTR Investigators</creatorcontrib><description>Aims
Data on the prognostic impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim of this analysis was to evaluate 2‐year survival and symptomatic outcomes of patients in relation to residual TR after T‐TEER.
Methods and results
Using the large European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) we investigated the impact of residual TR on 2‐year all‐cause mortality and New York Heart Association (NYHA) functional class at follow‐up. The study further identified predictors for residual TR ≥3+ using a logistic regression model. The study included a total of 1286 T‐TEER patients (mean age 78.0 ± 8.9 years, 53.6% female). TR was successfully reduced to ≤1+ in 42.4%, 2+ in 40.0% and 3+ in 14.9% of patients at discharge, while 2.8% remained with TR ≥4+ after the procedure. Residual TR ≥3+ was an independent multivariable predictor of 2‐year all‐cause mortality (hazard ratio 2.06, 95% confidence interval 1.30–3.26, p = 0.002). The prevalence of residual TR ≥3+ was four times higher in patients with higher baseline TR (vena contracta >11.1 mm) and more severe tricuspid valve tenting (tenting area >1.92 cm2). Of note, no survival difference was observed in patients with residual TR ≤1+ versus 2+ (76.2% vs. 73.1%, p = 0.461). The rate of NYHA functional class ≥III at follow‐up was significantly higher in patients with residual TR ≥3+ (52.4% vs. 40.5%, p < 0.001). Of note, the degree of TR reduction significantly correlated with the extent of symptomatic improvement (p = 0.012).
Conclusions
T‐TEER effectively reduced TR severity in the majority of patients. While residual TR ≥3+ was associated with worse outcomes, no differences were observed for residual TR 1+ versus 2+. Symptomatic improvement correlated with the degree of TR reduction.
Impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) (n = 1286). TV, tricuspid valve.</description><identifier>ISSN: 1388-9842</identifier><identifier>ISSN: 1879-0844</identifier><identifier>EISSN: 1879-0844</identifier><identifier>DOI: 10.1002/ejhf.3274</identifier><identifier>PMID: 38812292</identifier><language>eng</language><publisher>Oxford, UK: John Wiley & Sons, Ltd</publisher><subject>Procedural success ; Residual tricuspid regurgitation ; Tricuspid regurgitation ; Tricuspid regurgitation reduction</subject><ispartof>European journal of heart failure, 2024-08, Vol.26 (8), p.1850-1860</ispartof><rights>2024 The Authors. published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.</rights><rights>2024 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2904-c3ee5633659f2829ca4e4a701162a5a791936e3fffbcef6f26648b246c68b57c3</citedby><cites>FETCH-LOGICAL-c2904-c3ee5633659f2829ca4e4a701162a5a791936e3fffbcef6f26648b246c68b57c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fejhf.3274$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fejhf.3274$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38812292$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stolz, Lukas</creatorcontrib><creatorcontrib>Kresoja, Karl‐Patrik</creatorcontrib><creatorcontrib>Stein, Jennifer</creatorcontrib><creatorcontrib>Fortmeier, Vera</creatorcontrib><creatorcontrib>Koell, Benedikt</creatorcontrib><creatorcontrib>Rottbauer, Wolfgang</creatorcontrib><creatorcontrib>Kassar, Mohammad</creatorcontrib><creatorcontrib>Goebel, Bjoern</creatorcontrib><creatorcontrib>Denti, Paolo</creatorcontrib><creatorcontrib>Achouh, Paul</creatorcontrib><creatorcontrib>Rassaf, Tienush</creatorcontrib><creatorcontrib>Barreiro‐Perez, Manuel</creatorcontrib><creatorcontrib>Boekstegers, Peter</creatorcontrib><creatorcontrib>Rück, Andreas</creatorcontrib><creatorcontrib>Doldi, Philipp M.</creatorcontrib><creatorcontrib>Novotny, Julia</creatorcontrib><creatorcontrib>Zdanyte, Monika</creatorcontrib><creatorcontrib>Adamo, Marianna</creatorcontrib><creatorcontrib>Vincent, Flavien</creatorcontrib><creatorcontrib>Schlegel, Philipp</creatorcontrib><creatorcontrib>Bardeleben, Ralph‐Stephan</creatorcontrib><creatorcontrib>Stocker, Thomas J.</creatorcontrib><creatorcontrib>Weckbach, Ludwig T.</creatorcontrib><creatorcontrib>Wild, Mirjam G.</creatorcontrib><creatorcontrib>Brunner, Stephanie</creatorcontrib><creatorcontrib>Toggweiler, Stefan</creatorcontrib><creatorcontrib>Grapsa, Julia</creatorcontrib><creatorcontrib>Patterson, Tiffany</creatorcontrib><creatorcontrib>Thiele, Holger</creatorcontrib><creatorcontrib>Kister, Tobias</creatorcontrib><creatorcontrib>Konstandin, Mathias H.</creatorcontrib><creatorcontrib>Van Belle, Eric</creatorcontrib><creatorcontrib>Metra, Marco</creatorcontrib><creatorcontrib>Geisler, Tobias</creatorcontrib><creatorcontrib>Estévez‐Loureiro, Rodrigo</creatorcontrib><creatorcontrib>Luedike, Peter</creatorcontrib><creatorcontrib>Karam, Nicole</creatorcontrib><creatorcontrib>Maisano, Francesco</creatorcontrib><creatorcontrib>Lauten, Philipp</creatorcontrib><creatorcontrib>Praz, Fabien</creatorcontrib><creatorcontrib>Kessler, Mirjam</creatorcontrib><creatorcontrib>Kalbacher, Daniel</creatorcontrib><creatorcontrib>Rudolph, Volker</creatorcontrib><creatorcontrib>Iliadis, Christos</creatorcontrib><creatorcontrib>Lurz, Philipp</creatorcontrib><creatorcontrib>Hausleiter, Jörg</creatorcontrib><creatorcontrib>Pfister, Roman</creatorcontrib><creatorcontrib>Baldus, Stephan</creatorcontrib><creatorcontrib>Gerçek, Muhammed</creatorcontrib><creatorcontrib>Rudolph, Felix</creatorcontrib><creatorcontrib>Ludwig, Sebastian</creatorcontrib><creatorcontrib>Pauschinger, Christoph</creatorcontrib><creatorcontrib>Schneider, Leonhard‐Moritz</creatorcontrib><creatorcontrib>Felbel, Dominik</creatorcontrib><creatorcontrib>Salomon, Carsten</creatorcontrib><creatorcontrib>Lapp, Harald</creatorcontrib><creatorcontrib>Puscas, Tania</creatorcontrib><creatorcontrib>Berrebi, Alain</creatorcontrib><creatorcontrib>Mahabadi, Amir Abbas</creatorcontrib><creatorcontrib>Schindhelm, Florian</creatorcontrib><creatorcontrib>Caneiro‐Queija, Berenice</creatorcontrib><creatorcontrib>Echarte, Julio C</creatorcontrib><creatorcontrib>Schreieck, Jürgen</creatorcontrib><creatorcontrib>Goldschmied, Andreas</creatorcontrib><creatorcontrib>Pancaldi, Edoardo</creatorcontrib><creatorcontrib>Tomasoni, Daniela</creatorcontrib><creatorcontrib>Rousse, Natacha</creatorcontrib><creatorcontrib>Aghezzaf, Samy</creatorcontrib><creatorcontrib>Frey, Norbert</creatorcontrib><creatorcontrib>Kraus, Martin</creatorcontrib><creatorcontrib>Rosch, Sebastian</creatorcontrib><creatorcontrib>on behalf of the EuroTR Investigators</creatorcontrib><title>Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry</title><title>European journal of heart failure</title><addtitle>Eur J Heart Fail</addtitle><description>Aims
Data on the prognostic impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim of this analysis was to evaluate 2‐year survival and symptomatic outcomes of patients in relation to residual TR after T‐TEER.
Methods and results
Using the large European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) we investigated the impact of residual TR on 2‐year all‐cause mortality and New York Heart Association (NYHA) functional class at follow‐up. The study further identified predictors for residual TR ≥3+ using a logistic regression model. The study included a total of 1286 T‐TEER patients (mean age 78.0 ± 8.9 years, 53.6% female). TR was successfully reduced to ≤1+ in 42.4%, 2+ in 40.0% and 3+ in 14.9% of patients at discharge, while 2.8% remained with TR ≥4+ after the procedure. Residual TR ≥3+ was an independent multivariable predictor of 2‐year all‐cause mortality (hazard ratio 2.06, 95% confidence interval 1.30–3.26, p = 0.002). The prevalence of residual TR ≥3+ was four times higher in patients with higher baseline TR (vena contracta >11.1 mm) and more severe tricuspid valve tenting (tenting area >1.92 cm2). Of note, no survival difference was observed in patients with residual TR ≤1+ versus 2+ (76.2% vs. 73.1%, p = 0.461). The rate of NYHA functional class ≥III at follow‐up was significantly higher in patients with residual TR ≥3+ (52.4% vs. 40.5%, p < 0.001). Of note, the degree of TR reduction significantly correlated with the extent of symptomatic improvement (p = 0.012).
Conclusions
T‐TEER effectively reduced TR severity in the majority of patients. While residual TR ≥3+ was associated with worse outcomes, no differences were observed for residual TR 1+ versus 2+. Symptomatic improvement correlated with the degree of TR reduction.
Impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) (n = 1286). TV, tricuspid valve.</description><subject>Procedural success</subject><subject>Residual tricuspid regurgitation</subject><subject>Tricuspid regurgitation</subject><subject>Tricuspid regurgitation reduction</subject><issn>1388-9842</issn><issn>1879-0844</issn><issn>1879-0844</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><recordid>eNp1kEtOwzAQhi0EouWx4AIoS1iE-hUnYYeqloIqIaGyjhx33LpKk2I7Qt1xBM7ISXBoQWzYzIxmvvkWP0IXBN8QjOkAVkt9w2jKD1CfZGke44zzwzCzLIvzjNMeOnFuhTFJA36MemFPKM1pH22fwZl5K6vIW6NatzHzyMKitQvjpTdNHUntwf65eitrp6RfQreH-QI-3z98E0o3h-eNNPY2eqidWSy9i0ztmyjQ0ai1zey5sxvn7fYMHWlZOTjf91P0Mh7NhpN4-nT_MLybxormmMeKASSCMZHkmmY0V5IDlykmRFCZyDQnORPAtNalAi00FYJnJeVCiaxMUsVO0dXOu7HNawvOF2vjFFSVrKFpXcGwoAnjnKcBvd6hyjbOWdDFxpq1tNuC4KJLuuiSLrqkA3u517blGua_5E-0ARjsgDdTwfZ_UzF6nIy_lV8th4yo</recordid><startdate>202408</startdate><enddate>202408</enddate><creator>Stolz, Lukas</creator><creator>Kresoja, Karl‐Patrik</creator><creator>Stein, Jennifer</creator><creator>Fortmeier, Vera</creator><creator>Koell, Benedikt</creator><creator>Rottbauer, Wolfgang</creator><creator>Kassar, Mohammad</creator><creator>Goebel, Bjoern</creator><creator>Denti, Paolo</creator><creator>Achouh, Paul</creator><creator>Rassaf, Tienush</creator><creator>Barreiro‐Perez, Manuel</creator><creator>Boekstegers, Peter</creator><creator>Rück, Andreas</creator><creator>Doldi, Philipp M.</creator><creator>Novotny, Julia</creator><creator>Zdanyte, Monika</creator><creator>Adamo, Marianna</creator><creator>Vincent, Flavien</creator><creator>Schlegel, Philipp</creator><creator>Bardeleben, Ralph‐Stephan</creator><creator>Stocker, Thomas J.</creator><creator>Weckbach, Ludwig T.</creator><creator>Wild, Mirjam G.</creator><creator>Brunner, Stephanie</creator><creator>Toggweiler, Stefan</creator><creator>Grapsa, Julia</creator><creator>Patterson, Tiffany</creator><creator>Thiele, Holger</creator><creator>Kister, Tobias</creator><creator>Konstandin, Mathias H.</creator><creator>Van Belle, Eric</creator><creator>Metra, Marco</creator><creator>Geisler, Tobias</creator><creator>Estévez‐Loureiro, Rodrigo</creator><creator>Luedike, Peter</creator><creator>Karam, Nicole</creator><creator>Maisano, Francesco</creator><creator>Lauten, Philipp</creator><creator>Praz, Fabien</creator><creator>Kessler, Mirjam</creator><creator>Kalbacher, Daniel</creator><creator>Rudolph, Volker</creator><creator>Iliadis, Christos</creator><creator>Lurz, Philipp</creator><creator>Hausleiter, Jörg</creator><creator>Pfister, Roman</creator><creator>Baldus, Stephan</creator><creator>Gerçek, Muhammed</creator><creator>Rudolph, Felix</creator><creator>Ludwig, Sebastian</creator><creator>Pauschinger, Christoph</creator><creator>Schneider, Leonhard‐Moritz</creator><creator>Felbel, Dominik</creator><creator>Salomon, Carsten</creator><creator>Lapp, Harald</creator><creator>Puscas, Tania</creator><creator>Berrebi, Alain</creator><creator>Mahabadi, Amir Abbas</creator><creator>Schindhelm, Florian</creator><creator>Caneiro‐Queija, Berenice</creator><creator>Echarte, Julio C</creator><creator>Schreieck, Jürgen</creator><creator>Goldschmied, Andreas</creator><creator>Pancaldi, Edoardo</creator><creator>Tomasoni, Daniela</creator><creator>Rousse, Natacha</creator><creator>Aghezzaf, Samy</creator><creator>Frey, Norbert</creator><creator>Kraus, Martin</creator><creator>Rosch, Sebastian</creator><general>John Wiley & Sons, Ltd</general><scope>24P</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202408</creationdate><title>Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry</title><author>Stolz, Lukas ; Kresoja, Karl‐Patrik ; Stein, Jennifer ; Fortmeier, Vera ; Koell, Benedikt ; Rottbauer, Wolfgang ; Kassar, Mohammad ; Goebel, Bjoern ; Denti, Paolo ; Achouh, Paul ; Rassaf, Tienush ; Barreiro‐Perez, Manuel ; Boekstegers, Peter ; Rück, Andreas ; Doldi, Philipp M. ; Novotny, Julia ; Zdanyte, Monika ; Adamo, Marianna ; Vincent, Flavien ; Schlegel, Philipp ; Bardeleben, Ralph‐Stephan ; Stocker, Thomas J. ; Weckbach, Ludwig T. ; Wild, Mirjam G. ; Brunner, Stephanie ; Toggweiler, Stefan ; Grapsa, Julia ; Patterson, Tiffany ; Thiele, Holger ; Kister, Tobias ; Konstandin, Mathias H. ; Van Belle, Eric ; Metra, Marco ; Geisler, Tobias ; Estévez‐Loureiro, Rodrigo ; Luedike, Peter ; Karam, Nicole ; Maisano, Francesco ; Lauten, Philipp ; Praz, Fabien ; Kessler, Mirjam ; Kalbacher, Daniel ; Rudolph, Volker ; Iliadis, Christos ; Lurz, Philipp ; Hausleiter, Jörg ; Pfister, Roman ; Baldus, Stephan ; Gerçek, Muhammed ; Rudolph, Felix ; Ludwig, Sebastian ; Pauschinger, Christoph ; Schneider, Leonhard‐Moritz ; Felbel, Dominik ; Salomon, Carsten ; Lapp, Harald ; Puscas, Tania ; Berrebi, Alain ; Mahabadi, Amir Abbas ; Schindhelm, Florian ; Caneiro‐Queija, Berenice ; Echarte, Julio C ; Schreieck, Jürgen ; Goldschmied, Andreas ; Pancaldi, Edoardo ; Tomasoni, Daniela ; Rousse, Natacha ; Aghezzaf, Samy ; Frey, Norbert ; Kraus, Martin ; Rosch, Sebastian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2904-c3ee5633659f2829ca4e4a701162a5a791936e3fffbcef6f26648b246c68b57c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Procedural success</topic><topic>Residual tricuspid regurgitation</topic><topic>Tricuspid regurgitation</topic><topic>Tricuspid regurgitation reduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stolz, Lukas</creatorcontrib><creatorcontrib>Kresoja, Karl‐Patrik</creatorcontrib><creatorcontrib>Stein, Jennifer</creatorcontrib><creatorcontrib>Fortmeier, Vera</creatorcontrib><creatorcontrib>Koell, Benedikt</creatorcontrib><creatorcontrib>Rottbauer, Wolfgang</creatorcontrib><creatorcontrib>Kassar, Mohammad</creatorcontrib><creatorcontrib>Goebel, Bjoern</creatorcontrib><creatorcontrib>Denti, Paolo</creatorcontrib><creatorcontrib>Achouh, Paul</creatorcontrib><creatorcontrib>Rassaf, Tienush</creatorcontrib><creatorcontrib>Barreiro‐Perez, Manuel</creatorcontrib><creatorcontrib>Boekstegers, Peter</creatorcontrib><creatorcontrib>Rück, Andreas</creatorcontrib><creatorcontrib>Doldi, Philipp M.</creatorcontrib><creatorcontrib>Novotny, Julia</creatorcontrib><creatorcontrib>Zdanyte, Monika</creatorcontrib><creatorcontrib>Adamo, Marianna</creatorcontrib><creatorcontrib>Vincent, Flavien</creatorcontrib><creatorcontrib>Schlegel, Philipp</creatorcontrib><creatorcontrib>Bardeleben, Ralph‐Stephan</creatorcontrib><creatorcontrib>Stocker, Thomas J.</creatorcontrib><creatorcontrib>Weckbach, Ludwig T.</creatorcontrib><creatorcontrib>Wild, Mirjam G.</creatorcontrib><creatorcontrib>Brunner, Stephanie</creatorcontrib><creatorcontrib>Toggweiler, Stefan</creatorcontrib><creatorcontrib>Grapsa, Julia</creatorcontrib><creatorcontrib>Patterson, Tiffany</creatorcontrib><creatorcontrib>Thiele, Holger</creatorcontrib><creatorcontrib>Kister, Tobias</creatorcontrib><creatorcontrib>Konstandin, Mathias H.</creatorcontrib><creatorcontrib>Van Belle, Eric</creatorcontrib><creatorcontrib>Metra, Marco</creatorcontrib><creatorcontrib>Geisler, Tobias</creatorcontrib><creatorcontrib>Estévez‐Loureiro, Rodrigo</creatorcontrib><creatorcontrib>Luedike, Peter</creatorcontrib><creatorcontrib>Karam, Nicole</creatorcontrib><creatorcontrib>Maisano, Francesco</creatorcontrib><creatorcontrib>Lauten, Philipp</creatorcontrib><creatorcontrib>Praz, Fabien</creatorcontrib><creatorcontrib>Kessler, Mirjam</creatorcontrib><creatorcontrib>Kalbacher, Daniel</creatorcontrib><creatorcontrib>Rudolph, Volker</creatorcontrib><creatorcontrib>Iliadis, Christos</creatorcontrib><creatorcontrib>Lurz, Philipp</creatorcontrib><creatorcontrib>Hausleiter, Jörg</creatorcontrib><creatorcontrib>Pfister, Roman</creatorcontrib><creatorcontrib>Baldus, Stephan</creatorcontrib><creatorcontrib>Gerçek, Muhammed</creatorcontrib><creatorcontrib>Rudolph, Felix</creatorcontrib><creatorcontrib>Ludwig, Sebastian</creatorcontrib><creatorcontrib>Pauschinger, Christoph</creatorcontrib><creatorcontrib>Schneider, Leonhard‐Moritz</creatorcontrib><creatorcontrib>Felbel, Dominik</creatorcontrib><creatorcontrib>Salomon, Carsten</creatorcontrib><creatorcontrib>Lapp, Harald</creatorcontrib><creatorcontrib>Puscas, Tania</creatorcontrib><creatorcontrib>Berrebi, Alain</creatorcontrib><creatorcontrib>Mahabadi, Amir Abbas</creatorcontrib><creatorcontrib>Schindhelm, Florian</creatorcontrib><creatorcontrib>Caneiro‐Queija, Berenice</creatorcontrib><creatorcontrib>Echarte, Julio C</creatorcontrib><creatorcontrib>Schreieck, Jürgen</creatorcontrib><creatorcontrib>Goldschmied, Andreas</creatorcontrib><creatorcontrib>Pancaldi, Edoardo</creatorcontrib><creatorcontrib>Tomasoni, Daniela</creatorcontrib><creatorcontrib>Rousse, Natacha</creatorcontrib><creatorcontrib>Aghezzaf, Samy</creatorcontrib><creatorcontrib>Frey, Norbert</creatorcontrib><creatorcontrib>Kraus, Martin</creatorcontrib><creatorcontrib>Rosch, Sebastian</creatorcontrib><creatorcontrib>on behalf of the EuroTR Investigators</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of heart failure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stolz, Lukas</au><au>Kresoja, Karl‐Patrik</au><au>Stein, Jennifer</au><au>Fortmeier, Vera</au><au>Koell, Benedikt</au><au>Rottbauer, Wolfgang</au><au>Kassar, Mohammad</au><au>Goebel, Bjoern</au><au>Denti, Paolo</au><au>Achouh, Paul</au><au>Rassaf, Tienush</au><au>Barreiro‐Perez, Manuel</au><au>Boekstegers, Peter</au><au>Rück, Andreas</au><au>Doldi, Philipp M.</au><au>Novotny, Julia</au><au>Zdanyte, Monika</au><au>Adamo, Marianna</au><au>Vincent, Flavien</au><au>Schlegel, Philipp</au><au>Bardeleben, Ralph‐Stephan</au><au>Stocker, Thomas J.</au><au>Weckbach, Ludwig T.</au><au>Wild, Mirjam G.</au><au>Brunner, Stephanie</au><au>Toggweiler, Stefan</au><au>Grapsa, Julia</au><au>Patterson, Tiffany</au><au>Thiele, Holger</au><au>Kister, Tobias</au><au>Konstandin, Mathias H.</au><au>Van Belle, Eric</au><au>Metra, Marco</au><au>Geisler, Tobias</au><au>Estévez‐Loureiro, Rodrigo</au><au>Luedike, Peter</au><au>Karam, Nicole</au><au>Maisano, Francesco</au><au>Lauten, Philipp</au><au>Praz, Fabien</au><au>Kessler, Mirjam</au><au>Kalbacher, Daniel</au><au>Rudolph, Volker</au><au>Iliadis, Christos</au><au>Lurz, Philipp</au><au>Hausleiter, Jörg</au><au>Pfister, Roman</au><au>Baldus, Stephan</au><au>Gerçek, Muhammed</au><au>Rudolph, Felix</au><au>Ludwig, Sebastian</au><au>Pauschinger, Christoph</au><au>Schneider, Leonhard‐Moritz</au><au>Felbel, Dominik</au><au>Salomon, Carsten</au><au>Lapp, Harald</au><au>Puscas, Tania</au><au>Berrebi, Alain</au><au>Mahabadi, Amir Abbas</au><au>Schindhelm, Florian</au><au>Caneiro‐Queija, Berenice</au><au>Echarte, Julio C</au><au>Schreieck, Jürgen</au><au>Goldschmied, Andreas</au><au>Pancaldi, Edoardo</au><au>Tomasoni, Daniela</au><au>Rousse, Natacha</au><au>Aghezzaf, Samy</au><au>Frey, Norbert</au><au>Kraus, Martin</au><au>Rosch, Sebastian</au><aucorp>on behalf of the EuroTR Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry</atitle><jtitle>European journal of heart failure</jtitle><addtitle>Eur J Heart Fail</addtitle><date>2024-08</date><risdate>2024</risdate><volume>26</volume><issue>8</issue><spage>1850</spage><epage>1860</epage><pages>1850-1860</pages><issn>1388-9842</issn><issn>1879-0844</issn><eissn>1879-0844</eissn><abstract>Aims
Data on the prognostic impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim of this analysis was to evaluate 2‐year survival and symptomatic outcomes of patients in relation to residual TR after T‐TEER.
Methods and results
Using the large European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) we investigated the impact of residual TR on 2‐year all‐cause mortality and New York Heart Association (NYHA) functional class at follow‐up. The study further identified predictors for residual TR ≥3+ using a logistic regression model. The study included a total of 1286 T‐TEER patients (mean age 78.0 ± 8.9 years, 53.6% female). TR was successfully reduced to ≤1+ in 42.4%, 2+ in 40.0% and 3+ in 14.9% of patients at discharge, while 2.8% remained with TR ≥4+ after the procedure. Residual TR ≥3+ was an independent multivariable predictor of 2‐year all‐cause mortality (hazard ratio 2.06, 95% confidence interval 1.30–3.26, p = 0.002). The prevalence of residual TR ≥3+ was four times higher in patients with higher baseline TR (vena contracta >11.1 mm) and more severe tricuspid valve tenting (tenting area >1.92 cm2). Of note, no survival difference was observed in patients with residual TR ≤1+ versus 2+ (76.2% vs. 73.1%, p = 0.461). The rate of NYHA functional class ≥III at follow‐up was significantly higher in patients with residual TR ≥3+ (52.4% vs. 40.5%, p < 0.001). Of note, the degree of TR reduction significantly correlated with the extent of symptomatic improvement (p = 0.012).
Conclusions
T‐TEER effectively reduced TR severity in the majority of patients. While residual TR ≥3+ was associated with worse outcomes, no differences were observed for residual TR 1+ versus 2+. Symptomatic improvement correlated with the degree of TR reduction.
Impact of residual tricuspid regurgitation (TR) after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) (n = 1286). TV, tricuspid valve.</abstract><cop>Oxford, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>38812292</pmid><doi>10.1002/ejhf.3274</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1388-9842 |
| ispartof | European journal of heart failure, 2024-08, Vol.26 (8), p.1850-1860 |
| issn | 1388-9842 1879-0844 1879-0844 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3062534447 |
| source | Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | Procedural success Residual tricuspid regurgitation Tricuspid regurgitation Tricuspid regurgitation reduction |
| title | Residual tricuspid regurgitation after tricuspid transcatheter edge‐to‐edge repair: Insights into the EuroTR registry |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T19%3A43%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Residual%20tricuspid%20regurgitation%20after%20tricuspid%20transcatheter%20edge%E2%80%90to%E2%80%90edge%20repair:%20Insights%20into%20the%20EuroTR%20registry&rft.jtitle=European%20journal%20of%20heart%20failure&rft.au=Stolz,%20Lukas&rft.aucorp=on%20behalf%20of%20the%20EuroTR%20Investigators&rft.date=2024-08&rft.volume=26&rft.issue=8&rft.spage=1850&rft.epage=1860&rft.pages=1850-1860&rft.issn=1388-9842&rft.eissn=1879-0844&rft_id=info:doi/10.1002/ejhf.3274&rft_dat=%3Cproquest_cross%3E3062534447%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3062534447&rft_id=info:pmid/38812292&rfr_iscdi=true |