Seroprevalence and risk factors of Toxoplasma gondii infection among goats in Algeria
Toxoplasmosis is one of the most common zoonotic parasitic diseases worldwide and is caused by Toxoplasma gondii. It is implicated in reproductive disorders in small ruminants. This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infecti...
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| creator | Chettih, Ikram Abdellaoui, Lynda Mekroud, Meriem Dahmani, Ali Nabi, Mustapha Omar, Karima Hadj Touhami, Nadjet Amina Khelifi Dahmani, Hichem Bouasla, Lyes Ouchetati, Imane Belala, Redha Ouchene, Nassim |
| description | Toxoplasmosis is one of the most common zoonotic parasitic diseases worldwide and is caused by Toxoplasma gondii. It is implicated in reproductive disorders in small ruminants. This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats. The study was conducted in four regions, Ghardaia, Laghouat and Djelfa, southern Algeria, and Jijel region, northern Algeria. A total of 92 blood samples were collected including 74 females and 18 males. All sera were tested using an enzyme-linked immunosorbent assay (ELISA) to detect the T. gondii antibodies. The presence of anti-T. gondii antibodies was detected in 35 out of 92 goats (38.04%) (95% CI: 31.64%–44.44%) and in all flocks (100%). Risk factors that have a significant influence on the seroprevalence of T. gondii infection are breed, regions, production system, presence of cats, clinics and abortion history. However, variables such as age and gender were note significantly associated with toxoplasma infection in goats. The highest seroprevalences of infection was observed in saanen (52.94%) (p |
| doi_str_mv | 10.1016/j.cimid.2024.102201 |
| format | Article |
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•This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats.•A total of 92 blood samples were collected of which anti-T. gondii antibodies were detected in 38.04% goats and in all flocks (100%).•Factors such as breed, regions, production system, presence of cats, clinics, and abortion history have a significant impact on the seroprevalence of T. gondii infection. However, age and gender did not show significant associations.•These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans.]]></description><identifier>ISSN: 0147-9571</identifier><identifier>EISSN: 1878-1667</identifier><identifier>DOI: 10.1016/j.cimid.2024.102201</identifier><identifier>PMID: 38810337</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Algeria - epidemiology ; Animals ; Antibodies, Protozoan - blood ; Cats ; Enzyme-Linked Immunosorbent Assay ; Female ; Goat Diseases - epidemiology ; Goat Diseases - parasitology ; Goats ; Goats - parasitology ; Male ; Risk Factors ; Seroepidemiologic Studies ; Seroprevalence ; Toxoplasma - immunology ; Toxoplasmosis ; Toxoplasmosis, Animal - epidemiology ; Toxoplasmosis, Animal - parasitology</subject><ispartof>Comparative immunology, microbiology and infectious diseases, 2024-07, Vol.110, p.102201-102201, Article 102201</ispartof><rights>2024 Elsevier Ltd</rights><rights>Copyright © 2024 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c239t-9bf9ddf001b43285a34e36a84495c3fd3f8ca6ff70ab0c1f87b70ca8a96d8fae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.cimid.2024.102201$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38810337$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chettih, Ikram</creatorcontrib><creatorcontrib>Abdellaoui, Lynda</creatorcontrib><creatorcontrib>Mekroud, Meriem</creatorcontrib><creatorcontrib>Dahmani, Ali</creatorcontrib><creatorcontrib>Nabi, Mustapha</creatorcontrib><creatorcontrib>Omar, Karima Hadj</creatorcontrib><creatorcontrib>Touhami, Nadjet Amina Khelifi</creatorcontrib><creatorcontrib>Dahmani, Hichem</creatorcontrib><creatorcontrib>Bouasla, Lyes</creatorcontrib><creatorcontrib>Ouchetati, Imane</creatorcontrib><creatorcontrib>Belala, Redha</creatorcontrib><creatorcontrib>Ouchene, Nassim</creatorcontrib><title>Seroprevalence and risk factors of Toxoplasma gondii infection among goats in Algeria</title><title>Comparative immunology, microbiology and infectious diseases</title><addtitle>Comp Immunol Microbiol Infect Dis</addtitle><description><![CDATA[Toxoplasmosis is one of the most common zoonotic parasitic diseases worldwide and is caused by Toxoplasma gondii. It is implicated in reproductive disorders in small ruminants. This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats. The study was conducted in four regions, Ghardaia, Laghouat and Djelfa, southern Algeria, and Jijel region, northern Algeria. A total of 92 blood samples were collected including 74 females and 18 males. All sera were tested using an enzyme-linked immunosorbent assay (ELISA) to detect the T. gondii antibodies. The presence of anti-T. gondii antibodies was detected in 35 out of 92 goats (38.04%) (95% CI: 31.64%–44.44%) and in all flocks (100%). Risk factors that have a significant influence on the seroprevalence of T. gondii infection are breed, regions, production system, presence of cats, clinics and abortion history. However, variables such as age and gender were note significantly associated with toxoplasma infection in goats. The highest seroprevalences of infection was observed in saanen (52.94%) (p<0.001) and cross-breed race (44%) (p<0.01) in comparison with other breeds. Regarding regions, Jijel and Laghouat were most infected with seroprevalences of 50% (p<0.001) and 40.91% (p<0.01), respectively. Animals in intensive production systems were most infected, showing a seroprevalence of 51.85%, in comparison with extensive (28.13%) and semi-intensive systems (36.36%) (p<0.001). The presence of cats in farms was significantly associated with high seroprevalence (44.64%) (p<0.001). The infection was more prevalent in previously aborted females (50%) than females that had never aborted (3.35%) (p<0.001)and animals that have diarrhoea or poor health (41.67%) were significantly more infected than healthy animals (37.50%) (p<0.01). Seroprevalence in males (38.89%) was very close to those in females (37.84%) (p>0.05). Age-related seroprevalence did not vary significantly (ranged from 36.37% to 40%) between the three age classes. These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans. This requires more attention during consumption of goat meat.
•This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats.•A total of 92 blood samples were collected of which anti-T. gondii antibodies were detected in 38.04% goats and in all flocks (100%).•Factors such as breed, regions, production system, presence of cats, clinics, and abortion history have a significant impact on the seroprevalence of T. gondii infection. However, age and gender did not show significant associations.•These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans.]]></description><subject>Algeria - epidemiology</subject><subject>Animals</subject><subject>Antibodies, Protozoan - blood</subject><subject>Cats</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Goat Diseases - epidemiology</subject><subject>Goat Diseases - parasitology</subject><subject>Goats</subject><subject>Goats - parasitology</subject><subject>Male</subject><subject>Risk Factors</subject><subject>Seroepidemiologic Studies</subject><subject>Seroprevalence</subject><subject>Toxoplasma - immunology</subject><subject>Toxoplasmosis</subject><subject>Toxoplasmosis, Animal - epidemiology</subject><subject>Toxoplasmosis, Animal - parasitology</subject><issn>0147-9571</issn><issn>1878-1667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EoqXwBUjISzYpdpzEzoJFVfGSKrGgXVsTPyqXJC52WsHfk5LCktVIV-fOaA5C15RMKaHF3WaqXOP0NCVp1idpSugJGlPBRUKLgp-iMaEZT8qc0xG6iHFDCClpRs_RiAlBCWN8jFZvJvhtMHuoTasMhlbj4OI7tqA6HyL2Fi_9p9_WEBvAa99q57BrrVGd8y2GxrfrPoYu9ime1WsTHFyiMwt1NFfHOUGrx4fl_DlZvD69zGeLRKWs7JKysqXWlhBaZSwVObDMsAJElpW5YlYzKxQU1nICFVHUCl5xokBAWWhhwbAJuh32boP_2JnYycZFZeoaWuN3UTJSpDmjecp7lA2oCj7GYKzcBtdA-JKUyINPuZE_PuXBpxx89q2b44Fd1Rj91_kV2AP3A2D6N_fOBBmVO5jULvSKpPbu3wPfRQGITA</recordid><startdate>202407</startdate><enddate>202407</enddate><creator>Chettih, Ikram</creator><creator>Abdellaoui, Lynda</creator><creator>Mekroud, Meriem</creator><creator>Dahmani, Ali</creator><creator>Nabi, Mustapha</creator><creator>Omar, Karima Hadj</creator><creator>Touhami, Nadjet Amina Khelifi</creator><creator>Dahmani, Hichem</creator><creator>Bouasla, Lyes</creator><creator>Ouchetati, Imane</creator><creator>Belala, Redha</creator><creator>Ouchene, Nassim</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202407</creationdate><title>Seroprevalence and risk factors of Toxoplasma gondii infection among goats in Algeria</title><author>Chettih, Ikram ; Abdellaoui, Lynda ; Mekroud, Meriem ; Dahmani, Ali ; Nabi, Mustapha ; Omar, Karima Hadj ; Touhami, Nadjet Amina Khelifi ; Dahmani, Hichem ; Bouasla, Lyes ; Ouchetati, Imane ; Belala, Redha ; Ouchene, Nassim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c239t-9bf9ddf001b43285a34e36a84495c3fd3f8ca6ff70ab0c1f87b70ca8a96d8fae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Algeria - epidemiology</topic><topic>Animals</topic><topic>Antibodies, Protozoan - blood</topic><topic>Cats</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Goat Diseases - epidemiology</topic><topic>Goat Diseases - parasitology</topic><topic>Goats</topic><topic>Goats - parasitology</topic><topic>Male</topic><topic>Risk Factors</topic><topic>Seroepidemiologic Studies</topic><topic>Seroprevalence</topic><topic>Toxoplasma - immunology</topic><topic>Toxoplasmosis</topic><topic>Toxoplasmosis, Animal - epidemiology</topic><topic>Toxoplasmosis, Animal - parasitology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chettih, Ikram</creatorcontrib><creatorcontrib>Abdellaoui, Lynda</creatorcontrib><creatorcontrib>Mekroud, Meriem</creatorcontrib><creatorcontrib>Dahmani, Ali</creatorcontrib><creatorcontrib>Nabi, Mustapha</creatorcontrib><creatorcontrib>Omar, Karima Hadj</creatorcontrib><creatorcontrib>Touhami, Nadjet Amina Khelifi</creatorcontrib><creatorcontrib>Dahmani, Hichem</creatorcontrib><creatorcontrib>Bouasla, Lyes</creatorcontrib><creatorcontrib>Ouchetati, Imane</creatorcontrib><creatorcontrib>Belala, Redha</creatorcontrib><creatorcontrib>Ouchene, Nassim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Comparative immunology, microbiology and infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chettih, Ikram</au><au>Abdellaoui, Lynda</au><au>Mekroud, Meriem</au><au>Dahmani, Ali</au><au>Nabi, Mustapha</au><au>Omar, Karima Hadj</au><au>Touhami, Nadjet Amina Khelifi</au><au>Dahmani, Hichem</au><au>Bouasla, Lyes</au><au>Ouchetati, Imane</au><au>Belala, Redha</au><au>Ouchene, Nassim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seroprevalence and risk factors of Toxoplasma gondii infection among goats in Algeria</atitle><jtitle>Comparative immunology, microbiology and infectious diseases</jtitle><addtitle>Comp Immunol Microbiol Infect Dis</addtitle><date>2024-07</date><risdate>2024</risdate><volume>110</volume><spage>102201</spage><epage>102201</epage><pages>102201-102201</pages><artnum>102201</artnum><issn>0147-9571</issn><eissn>1878-1667</eissn><abstract><![CDATA[Toxoplasmosis is one of the most common zoonotic parasitic diseases worldwide and is caused by Toxoplasma gondii. It is implicated in reproductive disorders in small ruminants. This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats. The study was conducted in four regions, Ghardaia, Laghouat and Djelfa, southern Algeria, and Jijel region, northern Algeria. A total of 92 blood samples were collected including 74 females and 18 males. All sera were tested using an enzyme-linked immunosorbent assay (ELISA) to detect the T. gondii antibodies. The presence of anti-T. gondii antibodies was detected in 35 out of 92 goats (38.04%) (95% CI: 31.64%–44.44%) and in all flocks (100%). Risk factors that have a significant influence on the seroprevalence of T. gondii infection are breed, regions, production system, presence of cats, clinics and abortion history. However, variables such as age and gender were note significantly associated with toxoplasma infection in goats. The highest seroprevalences of infection was observed in saanen (52.94%) (p<0.001) and cross-breed race (44%) (p<0.01) in comparison with other breeds. Regarding regions, Jijel and Laghouat were most infected with seroprevalences of 50% (p<0.001) and 40.91% (p<0.01), respectively. Animals in intensive production systems were most infected, showing a seroprevalence of 51.85%, in comparison with extensive (28.13%) and semi-intensive systems (36.36%) (p<0.001). The presence of cats in farms was significantly associated with high seroprevalence (44.64%) (p<0.001). The infection was more prevalent in previously aborted females (50%) than females that had never aborted (3.35%) (p<0.001)and animals that have diarrhoea or poor health (41.67%) were significantly more infected than healthy animals (37.50%) (p<0.01). Seroprevalence in males (38.89%) was very close to those in females (37.84%) (p>0.05). Age-related seroprevalence did not vary significantly (ranged from 36.37% to 40%) between the three age classes. These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans. This requires more attention during consumption of goat meat.
•This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats.•A total of 92 blood samples were collected of which anti-T. gondii antibodies were detected in 38.04% goats and in all flocks (100%).•Factors such as breed, regions, production system, presence of cats, clinics, and abortion history have a significant impact on the seroprevalence of T. gondii infection. However, age and gender did not show significant associations.•These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans.]]></abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>38810337</pmid><doi>10.1016/j.cimid.2024.102201</doi><tpages>1</tpages></addata></record> |
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| ispartof | Comparative immunology, microbiology and infectious diseases, 2024-07, Vol.110, p.102201-102201, Article 102201 |
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| subjects | Algeria - epidemiology Animals Antibodies, Protozoan - blood Cats Enzyme-Linked Immunosorbent Assay Female Goat Diseases - epidemiology Goat Diseases - parasitology Goats Goats - parasitology Male Risk Factors Seroepidemiologic Studies Seroprevalence Toxoplasma - immunology Toxoplasmosis Toxoplasmosis, Animal - epidemiology Toxoplasmosis, Animal - parasitology |
| title | Seroprevalence and risk factors of Toxoplasma gondii infection among goats in Algeria |
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