FasL impacts Tgfb signaling in osteoblastic cells

Fas ligand (FasL, CD178) belongs to classical apoptotic molecules, however, recent evidence expands the spectrum of FasL functions into non-apoptotic processes which also applies for the bone. Tgfb subfamily members (Tgfb1, Tgfb2, Tgfb3) represent major components in osteogenic pathways and extracel...

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Veröffentlicht in:	Cells & development 2024-09, Vol.179, p.203929, Article 203929
Hauptverfasser:	Kratochvilova, Adela, Knopfova, Lucia, Gregorkova, Janka, Gruber, Reinhard, Janeckova, Eva, Chai, Yang, Matalova, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line ECM Fas ligand Fas Ligand Protein - metabolism Fosl2 MEF2 Transcription Factors - genetics MEF2 Transcription Factors - metabolism Mef2c Mice Osteoblasts - metabolism Prrx1 Signal Transduction Tgfb Transforming Growth Factor beta - metabolism Transforming Growth Factor beta1 - metabolism Transforming Growth Factor beta1 - pharmacology Transforming Growth Factor beta2 - metabolism Transforming Growth Factor beta2 - pharmacology Transforming Growth Factor beta3 - genetics Transforming Growth Factor beta3 - metabolism
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