A three-dimensional cell culture approach to investigate cytotoxic effects and production of inflammatory mediators by epoxy resin-based and calcium silicate-based endodontic sealer

Objectives The aim of the present study was to assess the cytocompatibility of epoxy resin-based AH Plus Jet (Dentsply De Trey, Konstanz, Germany), Sealer Plus (MK Life, Porto Alegre, Brazil), calcium silicate-based Bio-C Sealer (Angelus, Londrina, PR, Brazil), Sealer Plus BC (MK Life) and AH Plus B...

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Veröffentlicht in:	Clinical oral investigations 2024-05, Vol.28 (6), p.344, Article 344
Hauptverfasser:	Scelza, Miriam F.Z., Tavares, Sandro J.O., Scelza, Pantaleo, Ramos, Gabriel S., Lima Aboud, Lilian Rachel de, Piasecki, Lucila, Leite, Paulo Emílio C., Silva, Jéssica Dornelas da, Soares-Lima, Sheila Coelho, Alves, Gutemberg G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Calcium Compounds - pharmacology Cell culture Cell Culture Techniques, Three Dimensional - methods Cell Survival - drug effects Cell viability Cytokines Cytotoxicity Dentistry Down-regulation Endodontics Epoxy Resins Fluorescence microscopy Humans Inflammation Inflammation Mediators - metabolism IP-10 protein L-Lactate dehydrogenase Materials Testing Medicine Microscopy, Fluorescence Osteoblasts - drug effects RANTES Root Canal Filling Materials - pharmacology Root canals Sealing compounds Silicates - pharmacology Spheroids
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