Salmonella Typhimurium expansion in the inflamed murine gut is dependent on aspartate derived from ROS-mediated microbiota lysis

Inflammation boosts the availability of electron acceptors in the intestinal lumen, creating a favorable niche for pathogenic Enterobacteriaceae. However, the mechanisms linking intestinal inflammation-mediated changes in luminal metabolites and pathogen expansion remain unclear. Here, we show that...

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Veröffentlicht in:Cell host & microbe 2024-06, Vol.32 (6), p.887-899.e6
Hauptverfasser: Yoo, Woongjae, Shealy, Nicolas G., Zieba, Jacob K., Torres, Teresa P., Baltagulov, Madi, Thomas, Julia D., Shelton, Catherine D., McGovern, Anna G., Foegeding, Nora J., Olsan, Erin E., Byndloss, Mariana X.
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Sprache:eng
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