IRF11 synergizes with STAT1 and STAT2 to promote type I IFN production

Interferon regulatory factor 11 (IRF11), a fish specific member of IRF family, is a transcription factor known for its positive role in teleost antiviral defense by regulating IFN expression. Despite its recognized function, the precise mechanism of IRF11 in type I IFNs production remains largely un...

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Veröffentlicht in:	Fish & shellfish immunology 2024-07, Vol.150, p.109656, Article 109656
Hauptverfasser:	Jiao, Zhiyuan, Li, Wenxing, Xiang, Chao, Li, DongLi, Huang, Wenshu, Nie, Pin, Huang, Bei
Format:	Artikel
Sprache:	eng
Schlagworte:	IFN production Interferon regulatory factor IRF11 STATs
Online-Zugang:	Volltext
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