Basic leucine zipper transcription activators – tools to improve production and quality of human erythropoietin in Nicotiana benthamiana

Human erythropoietin (hEPO) is one of the most in‐demand biopharmaceuticals, however, its production is challenging. When produced in a plant expression system, hEPO results in extensive plant tissue damage and low expression. It is demonstrated that the modulation of the plant protein synthesis mac...

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Veröffentlicht in:Biotechnology journal 2024-05, Vol.19 (5), p.e2300715-n/a
Hauptverfasser: Wagner, Nazgul, Musiychuk, Konstantin, Shoji, Yoko, Tottey, Stephen, Streatfield, Stephen J., Fischer, Rainer, Yusibov, Vidadi
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Sprache:eng
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