Unravelling the role of autophagy in human dental pulp
Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modul...
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Veröffentlicht in: | Journal of oral and maxillofacial pathology : JOMFP 2024, Vol.28 (1), p.106-108 |
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container_title | Journal of oral and maxillofacial pathology : JOMFP |
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creator | Wakhloo, Tulika Kishore, Sanjeev Durgapal, Prashant |
description | Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modulator of pathogenesis. This article highlights the emerging role of autophagy in inflammation and regeneration of human dental pulp. It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions. |
doi_str_mv | 10.4103/jomfp.jomfp_197_23 |
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It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions.</description><subject>Apoptosis</subject><subject>Autophagy</subject><subject>Dental pulp</subject><subject>Health aspects</subject><subject>Immune clearance</subject><subject>Immune response</subject><subject>Inflammation</subject><subject>Organelles</subject><subject>Pathogens</subject><subject>Proteins</subject><subject>Therapeutic applications</subject><issn>0973-029X</issn><issn>1998-393X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNptkd1LwzAUxYMobk7_AR-k4Isvnbm9bZM8ivgFA18c7C2kbbJ1tElNW2H_vZ2bn8iFXG44v8OBQ8g50GkMFK_XrjbN9OOVIJiM8ICMQQgeosDFIRlTwTCkkViMyEnbrilNeJxEx2SEnFMaR2xM0rn16k1XVWmXQbfSgXeVDpwJVN-5ZqWWm6C0waqvlQ0KbTtVBU1fNafkyKiq1Wf7PSHz-7uX28dw9vzwdHszC3OkHMMoy9I4y7MUgcVpDEIxEXNBiwQRDdLCcEiLQjMGSg8HA1RZVvA0z03EMo4TcrXzbbx77XXbybps8yGustr1rUSa0sE5ARikl3-ka9d7O6STCABxwinwb9VSVVqW1rjOq3xrKm84JAkHxK3X9B_VMIWuy9xZbcrh_xcQ7YDcu7b12sjGl7XyGwlUbsuSu5p-ljVAF_vEfVbr4gv5bAffAadKkE8</recordid><startdate>2024</startdate><enddate>2024</enddate><creator>Wakhloo, Tulika</creator><creator>Kishore, Sanjeev</creator><creator>Durgapal, Prashant</creator><general>Medknow Publications and Media Pvt. 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source | Medknow Open Access Medical Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Apoptosis Autophagy Dental pulp Health aspects Immune clearance Immune response Inflammation Organelles Pathogens Proteins Therapeutic applications |
title | Unravelling the role of autophagy in human dental pulp |
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