Unravelling the role of autophagy in human dental pulp

Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modul...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of oral and maxillofacial pathology : JOMFP 2024, Vol.28 (1), p.106-108
Hauptverfasser: Wakhloo, Tulika, Kishore, Sanjeev, Durgapal, Prashant
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 108
container_issue 1
container_start_page 106
container_title Journal of oral and maxillofacial pathology : JOMFP
container_volume 28
creator Wakhloo, Tulika
Kishore, Sanjeev
Durgapal, Prashant
description Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modulator of pathogenesis. This article highlights the emerging role of autophagy in inflammation and regeneration of human dental pulp. It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions.
doi_str_mv 10.4103/jomfp.jomfp_197_23
format Article
fullrecord <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_3060746511</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A815581331</galeid><sourcerecordid>A815581331</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3083-2bb64bcb631746419a794890d5333f30df816dde771aedf8713abbd86ccf27b83</originalsourceid><addsrcrecordid>eNptkd1LwzAUxYMobk7_AR-k4Isvnbm9bZM8ivgFA18c7C2kbbJ1tElNW2H_vZ2bn8iFXG44v8OBQ8g50GkMFK_XrjbN9OOVIJiM8ICMQQgeosDFIRlTwTCkkViMyEnbrilNeJxEx2SEnFMaR2xM0rn16k1XVWmXQbfSgXeVDpwJVN-5ZqWWm6C0waqvlQ0KbTtVBU1fNafkyKiq1Wf7PSHz-7uX28dw9vzwdHszC3OkHMMoy9I4y7MUgcVpDEIxEXNBiwQRDdLCcEiLQjMGSg8HA1RZVvA0z03EMo4TcrXzbbx77XXbybps8yGustr1rUSa0sE5ARikl3-ka9d7O6STCABxwinwb9VSVVqW1rjOq3xrKm84JAkHxK3X9B_VMIWuy9xZbcrh_xcQ7YDcu7b12sjGl7XyGwlUbsuSu5p-ljVAF_vEfVbr4gv5bAffAadKkE8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3111458018</pqid></control><display><type>article</type><title>Unravelling the role of autophagy in human dental pulp</title><source>Medknow Open Access Medical Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Wakhloo, Tulika ; Kishore, Sanjeev ; Durgapal, Prashant</creator><creatorcontrib>Wakhloo, Tulika ; Kishore, Sanjeev ; Durgapal, Prashant</creatorcontrib><description>Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modulator of pathogenesis. This article highlights the emerging role of autophagy in inflammation and regeneration of human dental pulp. It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions.</description><identifier>ISSN: 0973-029X</identifier><identifier>EISSN: 1998-393X</identifier><identifier>DOI: 10.4103/jomfp.jomfp_197_23</identifier><identifier>PMID: 38800427</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Apoptosis ; Autophagy ; Dental pulp ; Health aspects ; Immune clearance ; Immune response ; Inflammation ; Organelles ; Pathogens ; Proteins ; Therapeutic applications</subject><ispartof>Journal of oral and maxillofacial pathology : JOMFP, 2024, Vol.28 (1), p.106-108</ispartof><rights>Copyright: © 2024 Journal of Oral and Maxillofacial Pathology.</rights><rights>COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd.</rights><rights>2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3083-2bb64bcb631746419a794890d5333f30df816dde771aedf8713abbd86ccf27b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38800427$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wakhloo, Tulika</creatorcontrib><creatorcontrib>Kishore, Sanjeev</creatorcontrib><creatorcontrib>Durgapal, Prashant</creatorcontrib><title>Unravelling the role of autophagy in human dental pulp</title><title>Journal of oral and maxillofacial pathology : JOMFP</title><addtitle>J Oral Maxillofac Pathol</addtitle><description>Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modulator of pathogenesis. This article highlights the emerging role of autophagy in inflammation and regeneration of human dental pulp. It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions.</description><subject>Apoptosis</subject><subject>Autophagy</subject><subject>Dental pulp</subject><subject>Health aspects</subject><subject>Immune clearance</subject><subject>Immune response</subject><subject>Inflammation</subject><subject>Organelles</subject><subject>Pathogens</subject><subject>Proteins</subject><subject>Therapeutic applications</subject><issn>0973-029X</issn><issn>1998-393X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNptkd1LwzAUxYMobk7_AR-k4Isvnbm9bZM8ivgFA18c7C2kbbJ1tElNW2H_vZ2bn8iFXG44v8OBQ8g50GkMFK_XrjbN9OOVIJiM8ICMQQgeosDFIRlTwTCkkViMyEnbrilNeJxEx2SEnFMaR2xM0rn16k1XVWmXQbfSgXeVDpwJVN-5ZqWWm6C0waqvlQ0KbTtVBU1fNafkyKiq1Wf7PSHz-7uX28dw9vzwdHszC3OkHMMoy9I4y7MUgcVpDEIxEXNBiwQRDdLCcEiLQjMGSg8HA1RZVvA0z03EMo4TcrXzbbx77XXbybps8yGustr1rUSa0sE5ARikl3-ka9d7O6STCABxwinwb9VSVVqW1rjOq3xrKm84JAkHxK3X9B_VMIWuy9xZbcrh_xcQ7YDcu7b12sjGl7XyGwlUbsuSu5p-ljVAF_vEfVbr4gv5bAffAadKkE8</recordid><startdate>2024</startdate><enddate>2024</enddate><creator>Wakhloo, Tulika</creator><creator>Kishore, Sanjeev</creator><creator>Durgapal, Prashant</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt. Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>2024</creationdate><title>Unravelling the role of autophagy in human dental pulp</title><author>Wakhloo, Tulika ; Kishore, Sanjeev ; Durgapal, Prashant</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3083-2bb64bcb631746419a794890d5333f30df816dde771aedf8713abbd86ccf27b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Apoptosis</topic><topic>Autophagy</topic><topic>Dental pulp</topic><topic>Health aspects</topic><topic>Immune clearance</topic><topic>Immune response</topic><topic>Inflammation</topic><topic>Organelles</topic><topic>Pathogens</topic><topic>Proteins</topic><topic>Therapeutic applications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wakhloo, Tulika</creatorcontrib><creatorcontrib>Kishore, Sanjeev</creatorcontrib><creatorcontrib>Durgapal, Prashant</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of oral and maxillofacial pathology : JOMFP</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wakhloo, Tulika</au><au>Kishore, Sanjeev</au><au>Durgapal, Prashant</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Unravelling the role of autophagy in human dental pulp</atitle><jtitle>Journal of oral and maxillofacial pathology : JOMFP</jtitle><addtitle>J Oral Maxillofac Pathol</addtitle><date>2024</date><risdate>2024</risdate><volume>28</volume><issue>1</issue><spage>106</spage><epage>108</epage><pages>106-108</pages><issn>0973-029X</issn><eissn>1998-393X</eissn><abstract>Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammation, immune response and pathogen clearance and acts as a modulator of pathogenesis. This article highlights the emerging role of autophagy in inflammation and regeneration of human dental pulp. It emphasizes exploring autophagy and autophagy agonists as potential targets for the development of novel therapeutic interventions.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>38800427</pmid><doi>10.4103/jomfp.jomfp_197_23</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0973-029X
ispartof Journal of oral and maxillofacial pathology : JOMFP, 2024, Vol.28 (1), p.106-108
issn 0973-029X
1998-393X
language eng
recordid cdi_proquest_miscellaneous_3060746511
source Medknow Open Access Medical Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Apoptosis
Autophagy
Dental pulp
Health aspects
Immune clearance
Immune response
Inflammation
Organelles
Pathogens
Proteins
Therapeutic applications
title Unravelling the role of autophagy in human dental pulp
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T05%3A27%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Unravelling%20the%20role%20of%20autophagy%20in%20human%20dental%20pulp&rft.jtitle=Journal%20of%20oral%20and%20maxillofacial%20pathology%20:%20JOMFP&rft.au=Wakhloo,%20Tulika&rft.date=2024&rft.volume=28&rft.issue=1&rft.spage=106&rft.epage=108&rft.pages=106-108&rft.issn=0973-029X&rft.eissn=1998-393X&rft_id=info:doi/10.4103/jomfp.jomfp_197_23&rft_dat=%3Cgale_proqu%3EA815581331%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3111458018&rft_id=info:pmid/38800427&rft_galeid=A815581331&rfr_iscdi=true