Medication‐related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data

Purpose This study aimed to perform a nationwide analysis of medication errors (MEs) from hospitals using national reporting system data and to compare the ME patterns among different age groups. Methods We analyzed medication‐related incidents in acute care hospitals reported to the Korean Patient...

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Veröffentlicht in:Pharmacoepidemiology and drug safety 2024-06, Vol.33 (6), p.e5819-n/a
Hauptverfasser: Han, Ji Min, Heo, Kyu‐Nam, Kim, A Jeong, Lee, Ah Young, Min, Sangil, Ah, Young‐Mi, Lee, Ju‐Yeun
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container_issue 6
container_start_page e5819
container_title Pharmacoepidemiology and drug safety
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creator Han, Ji Min
Heo, Kyu‐Nam
Kim, A Jeong
Lee, Ah Young
Min, Sangil
Ah, Young‐Mi
Lee, Ju‐Yeun
description Purpose This study aimed to perform a nationwide analysis of medication errors (MEs) from hospitals using national reporting system data and to compare the ME patterns among different age groups. Methods We analyzed medication‐related incidents in acute care hospitals reported to the Korean Patient Safety Reporting and Learning System (KOPS), which is a patient safety reporting system, from July 2016 to December 2020. The stages of the medication use process, type of errors, medication class involved in MEs, and degree of harm were analyzed. Results Among a total of 5071 medication‐related incidents, 37.7% (1911 cases) were incidents that caused patient harm and 1.2% caused long‐term, permanent, and fatal harm. The proportion of medication‐related incidents that resulted in harm was the highest among the
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Methods We analyzed medication‐related incidents in acute care hospitals reported to the Korean Patient Safety Reporting and Learning System (KOPS), which is a patient safety reporting system, from July 2016 to December 2020. The stages of the medication use process, type of errors, medication class involved in MEs, and degree of harm were analyzed. Results Among a total of 5071 medication‐related incidents, 37.7% (1911 cases) were incidents that caused patient harm and 1.2% caused long‐term, permanent, and fatal harm. The proportion of medication‐related incidents that resulted in harm was the highest among the &lt;1‐year‐old age group (67 cases, 51.5%), followed by the elderly (≥ 65 years) (828 cases, 40.9%). The cases leading to patient death were most frequently reported in patients aged ≥65 years. Medication‐related incidents occurred mainly in the administration stage (2954 cases, 58.3%), and wrong dose was the most frequently reported ME type. The most prevalent medication class occurring in the 20–64‐year age group (256 cases, 11.7%) was ‘antibacterials for systemic use’, whereas ‘contrast media’ (236 cases, 11.6%) and ‘blood substitutes and perfusion solutions’ (98 cases, 19.3%) were the most prevalent drug classes in the ≥65‐ and &lt;20‐year‐old age groups, respectively. Conclusions It is necessary to establish guidelines for the prevention of medication‐related incidents according to the medication use process and patient age group.</description><identifier>ISSN: 1053-8569</identifier><identifier>ISSN: 1099-1557</identifier><identifier>EISSN: 1099-1557</identifier><identifier>DOI: 10.1002/pds.5819</identifier><identifier>PMID: 38783417</identifier><language>eng</language><publisher>Chichester, UK: John Wiley &amp; Sons, Inc</publisher><subject>Adolescent ; Adult ; adverse drug reaction reporting systems ; Adverse Drug Reaction Reporting Systems - statistics &amp; numerical data ; Age Factors ; Age groups ; Aged ; Aged, 80 and over ; Blood substitutes ; Child ; Child, Preschool ; Contrast media ; Drug-Related Side Effects and Adverse Reactions - epidemiology ; drug‐related side effects and adverse reaction ; Female ; Hospitals ; Hospitals - statistics &amp; numerical data ; Humans ; Infant ; Male ; medication errors ; Medication Errors - statistics &amp; numerical data ; Middle Aged ; Patient safety ; Patient Safety - statistics &amp; numerical data ; Republic of Korea - epidemiology ; Safety ; Young Adult</subject><ispartof>Pharmacoepidemiology and drug safety, 2024-06, Vol.33 (6), p.e5819-n/a</ispartof><rights>2024 The Authors. published by John Wiley &amp; Sons Ltd.</rights><rights>2024 The Authors. Pharmacoepidemiology and Drug Safety published by John Wiley &amp; Sons Ltd.</rights><rights>2024. This article is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3449-58e29e7d09639ed6c496eed57dc687f396509aed91993d618e1c32de54695b8e3</cites><orcidid>0000-0002-2261-7330</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpds.5819$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpds.5819$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38783417$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Han, Ji Min</creatorcontrib><creatorcontrib>Heo, Kyu‐Nam</creatorcontrib><creatorcontrib>Kim, A Jeong</creatorcontrib><creatorcontrib>Lee, Ah Young</creatorcontrib><creatorcontrib>Min, Sangil</creatorcontrib><creatorcontrib>Ah, Young‐Mi</creatorcontrib><creatorcontrib>Lee, Ju‐Yeun</creatorcontrib><title>Medication‐related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data</title><title>Pharmacoepidemiology and drug safety</title><addtitle>Pharmacoepidemiol Drug Saf</addtitle><description>Purpose This study aimed to perform a nationwide analysis of medication errors (MEs) from hospitals using national reporting system data and to compare the ME patterns among different age groups. Methods We analyzed medication‐related incidents in acute care hospitals reported to the Korean Patient Safety Reporting and Learning System (KOPS), which is a patient safety reporting system, from July 2016 to December 2020. The stages of the medication use process, type of errors, medication class involved in MEs, and degree of harm were analyzed. Results Among a total of 5071 medication‐related incidents, 37.7% (1911 cases) were incidents that caused patient harm and 1.2% caused long‐term, permanent, and fatal harm. The proportion of medication‐related incidents that resulted in harm was the highest among the &lt;1‐year‐old age group (67 cases, 51.5%), followed by the elderly (≥ 65 years) (828 cases, 40.9%). The cases leading to patient death were most frequently reported in patients aged ≥65 years. Medication‐related incidents occurred mainly in the administration stage (2954 cases, 58.3%), and wrong dose was the most frequently reported ME type. The most prevalent medication class occurring in the 20–64‐year age group (256 cases, 11.7%) was ‘antibacterials for systemic use’, whereas ‘contrast media’ (236 cases, 11.6%) and ‘blood substitutes and perfusion solutions’ (98 cases, 19.3%) were the most prevalent drug classes in the ≥65‐ and &lt;20‐year‐old age groups, respectively. Conclusions It is necessary to establish guidelines for the prevention of medication‐related incidents according to the medication use process and patient age group.</description><subject>Adolescent</subject><subject>Adult</subject><subject>adverse drug reaction reporting systems</subject><subject>Adverse Drug Reaction Reporting Systems - statistics &amp; numerical data</subject><subject>Age Factors</subject><subject>Age groups</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood substitutes</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Contrast media</subject><subject>Drug-Related Side Effects and Adverse Reactions - epidemiology</subject><subject>drug‐related side effects and adverse reaction</subject><subject>Female</subject><subject>Hospitals</subject><subject>Hospitals - statistics &amp; numerical data</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>medication errors</subject><subject>Medication Errors - statistics &amp; numerical data</subject><subject>Middle Aged</subject><subject>Patient safety</subject><subject>Patient Safety - statistics &amp; numerical data</subject><subject>Republic of Korea - epidemiology</subject><subject>Safety</subject><subject>Young Adult</subject><issn>1053-8569</issn><issn>1099-1557</issn><issn>1099-1557</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp1kU1LHTEUhoNY_Lgt-Ask4KabscnNJDPHnWjVgqWC7XqIyZlrZO5kTDLI3bnp3t_YX9LM1SoIXeWFPOc5HF5C9jg75IzNvww2HsqawwbZ4Qyg4FJWm1OWoqilgm2yG-MdY_kPyi2yLeqqFiWvdsjv72id0cn5_s_jU8BOJ7TU9cZZ7FPMiWozJqRGB6S3Pg4u6S5SvfT9glrXthgySPUC6SL4cYhH9DjP9LpbRRepb2m_tuuODjlMbNQtphUNOPiQqNVJfyQf2mzFTy_vjPw6-_rz5KK4_HH-7eT4sjCiLKGQNc4BK8tACUCrTAkK0crKGlVXrQAlGWi0wAGEVbxGbsTcoiwVyJsaxYx8fvYOwd-PGFOzdNFg1-ke_RgbwRQTFYhSZfTgHXrnx5DPmKiKSZB5-ZvQBB9jwLYZglvqsGo4a6ZqmlxNM1WT0f0X4XizRPsK_usiA8Uz8OA6XP1X1FydXq-FfwG3LZoV</recordid><startdate>202406</startdate><enddate>202406</enddate><creator>Han, Ji Min</creator><creator>Heo, Kyu‐Nam</creator><creator>Kim, A Jeong</creator><creator>Lee, Ah Young</creator><creator>Min, Sangil</creator><creator>Ah, Young‐Mi</creator><creator>Lee, Ju‐Yeun</creator><general>John Wiley &amp; Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2261-7330</orcidid></search><sort><creationdate>202406</creationdate><title>Medication‐related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data</title><author>Han, Ji Min ; Heo, Kyu‐Nam ; Kim, A Jeong ; Lee, Ah Young ; Min, Sangil ; Ah, Young‐Mi ; Lee, Ju‐Yeun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3449-58e29e7d09639ed6c496eed57dc687f396509aed91993d618e1c32de54695b8e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>adverse drug reaction reporting systems</topic><topic>Adverse Drug Reaction Reporting Systems - statistics &amp; numerical data</topic><topic>Age Factors</topic><topic>Age groups</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blood substitutes</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Contrast media</topic><topic>Drug-Related Side Effects and Adverse Reactions - epidemiology</topic><topic>drug‐related side effects and adverse reaction</topic><topic>Female</topic><topic>Hospitals</topic><topic>Hospitals - statistics &amp; numerical data</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>medication errors</topic><topic>Medication Errors - statistics &amp; numerical data</topic><topic>Middle Aged</topic><topic>Patient safety</topic><topic>Patient Safety - statistics &amp; numerical data</topic><topic>Republic of Korea - epidemiology</topic><topic>Safety</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Han, Ji Min</creatorcontrib><creatorcontrib>Heo, Kyu‐Nam</creatorcontrib><creatorcontrib>Kim, A Jeong</creatorcontrib><creatorcontrib>Lee, Ah Young</creatorcontrib><creatorcontrib>Min, Sangil</creatorcontrib><creatorcontrib>Ah, Young‐Mi</creatorcontrib><creatorcontrib>Lee, Ju‐Yeun</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacoepidemiology and drug safety</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Han, Ji Min</au><au>Heo, Kyu‐Nam</au><au>Kim, A Jeong</au><au>Lee, Ah Young</au><au>Min, Sangil</au><au>Ah, Young‐Mi</au><au>Lee, Ju‐Yeun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Medication‐related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data</atitle><jtitle>Pharmacoepidemiology and drug safety</jtitle><addtitle>Pharmacoepidemiol Drug Saf</addtitle><date>2024-06</date><risdate>2024</risdate><volume>33</volume><issue>6</issue><spage>e5819</spage><epage>n/a</epage><pages>e5819-n/a</pages><issn>1053-8569</issn><issn>1099-1557</issn><eissn>1099-1557</eissn><abstract>Purpose This study aimed to perform a nationwide analysis of medication errors (MEs) from hospitals using national reporting system data and to compare the ME patterns among different age groups. Methods We analyzed medication‐related incidents in acute care hospitals reported to the Korean Patient Safety Reporting and Learning System (KOPS), which is a patient safety reporting system, from July 2016 to December 2020. The stages of the medication use process, type of errors, medication class involved in MEs, and degree of harm were analyzed. Results Among a total of 5071 medication‐related incidents, 37.7% (1911 cases) were incidents that caused patient harm and 1.2% caused long‐term, permanent, and fatal harm. The proportion of medication‐related incidents that resulted in harm was the highest among the &lt;1‐year‐old age group (67 cases, 51.5%), followed by the elderly (≥ 65 years) (828 cases, 40.9%). The cases leading to patient death were most frequently reported in patients aged ≥65 years. Medication‐related incidents occurred mainly in the administration stage (2954 cases, 58.3%), and wrong dose was the most frequently reported ME type. The most prevalent medication class occurring in the 20–64‐year age group (256 cases, 11.7%) was ‘antibacterials for systemic use’, whereas ‘contrast media’ (236 cases, 11.6%) and ‘blood substitutes and perfusion solutions’ (98 cases, 19.3%) were the most prevalent drug classes in the ≥65‐ and &lt;20‐year‐old age groups, respectively. Conclusions It is necessary to establish guidelines for the prevention of medication‐related incidents according to the medication use process and patient age group.</abstract><cop>Chichester, UK</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>38783417</pmid><doi>10.1002/pds.5819</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-2261-7330</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
adverse drug reaction reporting systems
Adverse Drug Reaction Reporting Systems - statistics & numerical data
Age Factors
Age groups
Aged
Aged, 80 and over
Blood substitutes
Child
Child, Preschool
Contrast media
Drug-Related Side Effects and Adverse Reactions - epidemiology
drug‐related side effects and adverse reaction
Female
Hospitals
Hospitals - statistics & numerical data
Humans
Infant
Male
medication errors
Medication Errors - statistics & numerical data
Middle Aged
Patient safety
Patient Safety - statistics & numerical data
Republic of Korea - epidemiology
Safety
Young Adult
title Medication‐related incidents in acute care hospitals among different age groups: An analysis of national patient safety report data
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