Patterns of Early Neocortical Amyloid-β Accumulation: A PET Population-Based Study

The widespread deposition of amyloid-β (Aβ) plaques in late-stage Alzheimer disease is well defined and confirmed by in vivo PET. However, there are discrepancies between which regions contribute to the earliest topographic Aβ deposition within the neocortex. This study investigated Aβ signals in th...

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Veröffentlicht in:	Journal of Nuclear Medicine 2024-07, Vol.65 (7), p.1122-1128
Hauptverfasser:	Lecy, Emily E, Min, Hoon-Ki, Apgar, Christopher J, Maltais, Daniela D, Lundt, Emily S, Albertson, Sabrina M, Senjem, Matthew L, Schwarz, Christopher G, Botha, Hugo, Graff-Radford, Jonathan, Jones, David T, Vemuri, Prashanthi, Kantarci, Kejal, Knopman, David S, Petersen, Ronald C, Jack, Jr, Clifford R, Lee, Jeyeon, Lowe, Val J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apolipoproteins Cerebral cortex Cluster analysis Clustering Deposition In vivo methods and tests Neocortex Neurodegenerative diseases Phenotypes Population studies Positron emission Regional development β-Amyloid
Online-Zugang:	Volltext
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