Increased coexpression of PD-L1 and IDO1 is associated with poor overall survival in patients with NK/T-cell lymphoma

Immunotherapy with programmed cell death 1 ligand 1 (PD-L1) blockade was effective in patients with NK/T-cell lymphoma. In addition to PD-L1, indoleamine 2,3-dioxygenase-1 (IDO1) is one of the most promising immunotherapeutic targets. High proportions of PD-L1 and IDO1 proteins were observed by immu...

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Veröffentlicht in:	Leukemia 2024-07, Vol.38 (7), p.1553-1563
Hauptverfasser:	Li, Yajun, Chen, Kailin, Chen, Bihua, Zeng, Ruolan, He, Yizi, Wang, Caiqin, Zhong, Meizuo, Liu, Xianling, Chen, Xiaoyan, Xiao, Ling, Zhou, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	692/499 692/699/1541/1990/291/1621/1916 82/51 Adult Aged Aged, 80 and over Apoptosis B7-H1 Antigen - metabolism Biomarkers, Tumor - metabolism Cancer Research CD4 antigen Cell death Critical Care Medicine Female Follow-Up Studies Hematology Humans Immune checkpoint inhibitors Immunohistochemistry Immunotherapy Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism Intensive Internal Medicine Lymphocytes T Lymphoma Lymphoma, Extranodal NK-T-Cell - drug therapy Lymphoma, Extranodal NK-T-Cell - metabolism Lymphoma, Extranodal NK-T-Cell - mortality Lymphoma, Extranodal NK-T-Cell - pathology Male Medicine Medicine & Public Health Middle Aged Nomograms Oncology PD-L1 protein Prognosis Risk groups Survival Survival Rate T-cell lymphoma Tryptophan 2,3-dioxygenase Young Adult
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