Clinical Results of the MINIject Implant for Suprachoroidal Drainage
This retrospective study evaluated the safety and efficacy of the new minimally invasive MINIject implant placed in the suprachoroidal space. The aim was to assess its impact on intraocular pressure (IOP) reduction and complication rate. 18 eyes from 18 patients with insufficiently controlled glauco...
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| Veröffentlicht in: | Journal of clinical medicine 2024-05, Vol.13 (10), p.2831 |
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| creator | Gläser, Timothy Böhringer, Daniel Evers, Charlotte Keye, Philip Reinhard, Thomas Lübke, Jan |
| description | This retrospective study evaluated the safety and efficacy of the new minimally invasive MINIject implant placed in the suprachoroidal space. The aim was to assess its impact on intraocular pressure (IOP) reduction and complication rate.
18 eyes from 18 patients with insufficiently controlled glaucoma received the implant using topical medications. Outcomes were changes in IOP, change in IOP medication, need for other glaucoma surgery, and rate of adverse events.
IOP reduced by 15% (
< 0.05) following MINIject implantation. IOP medication decreased from 3 to 1 agent (
< 0.05). Four patients (22%) required other glaucoma surgery while we did not observe any clinically relevant adverse event.
This retrospective study indicates that MINIject implants may be a safe and effective means of reducing IOP together with a reduction in IOP medications in most patients. Larger prospective studies with longer follow-ups are necessary to confirm our results, though. |
| doi_str_mv | 10.3390/jcm13102831 |
| format | Article |
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18 eyes from 18 patients with insufficiently controlled glaucoma received the implant using topical medications. Outcomes were changes in IOP, change in IOP medication, need for other glaucoma surgery, and rate of adverse events.
IOP reduced by 15% (
< 0.05) following MINIject implantation. IOP medication decreased from 3 to 1 agent (
< 0.05). Four patients (22%) required other glaucoma surgery while we did not observe any clinically relevant adverse event.
This retrospective study indicates that MINIject implants may be a safe and effective means of reducing IOP together with a reduction in IOP medications in most patients. Larger prospective studies with longer follow-ups are necessary to confirm our results, though.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm13102831</identifier><identifier>PMID: 38792373</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Automation ; Care and treatment ; Diagnosis ; Eye ; Eye surgery ; Glaucoma ; Patients ; Regression analysis ; Surgery ; Survival analysis ; Topical medication ; Transplants & implants ; Visual acuity</subject><ispartof>Journal of clinical medicine, 2024-05, Vol.13 (10), p.2831</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c309t-646dc7355d69f24ef339b4779774d605b8e8229074f9235ebe8ab006ad4c80e03</cites><orcidid>0000-0002-3946-5759 ; 0000-0001-8307-5267</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38792373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gläser, Timothy</creatorcontrib><creatorcontrib>Böhringer, Daniel</creatorcontrib><creatorcontrib>Evers, Charlotte</creatorcontrib><creatorcontrib>Keye, Philip</creatorcontrib><creatorcontrib>Reinhard, Thomas</creatorcontrib><creatorcontrib>Lübke, Jan</creatorcontrib><title>Clinical Results of the MINIject Implant for Suprachoroidal Drainage</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>This retrospective study evaluated the safety and efficacy of the new minimally invasive MINIject implant placed in the suprachoroidal space. The aim was to assess its impact on intraocular pressure (IOP) reduction and complication rate.
18 eyes from 18 patients with insufficiently controlled glaucoma received the implant using topical medications. Outcomes were changes in IOP, change in IOP medication, need for other glaucoma surgery, and rate of adverse events.
IOP reduced by 15% (
< 0.05) following MINIject implantation. IOP medication decreased from 3 to 1 agent (
< 0.05). Four patients (22%) required other glaucoma surgery while we did not observe any clinically relevant adverse event.
This retrospective study indicates that MINIject implants may be a safe and effective means of reducing IOP together with a reduction in IOP medications in most patients. Larger prospective studies with longer follow-ups are necessary to confirm our results, though.</description><subject>Automation</subject><subject>Care and treatment</subject><subject>Diagnosis</subject><subject>Eye</subject><subject>Eye surgery</subject><subject>Glaucoma</subject><subject>Patients</subject><subject>Regression analysis</subject><subject>Surgery</subject><subject>Survival analysis</subject><subject>Topical medication</subject><subject>Transplants & implants</subject><subject>Visual acuity</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkc1P3DAQxa2KqiDg1HsVqZdKaGHsSWL7iJavlWiRaHuOHGcMXiXx1k4O_Pd4BQVaYR88sn7v6Y0eY585HCNqOFnbgSMHoZB_YHsCpFwAKtx5M--yw5TWkI9SpeDyE9tFJbVAiXvsbNn70VvTF7eU5n5KRXDFdE_F99WP1ZrsVKyGTW_GqXAhFj_nTTT2PsTguyw5i8aP5o4O2Edn-kSHz-8--31x_mt5tbi-uVwtT68XFkFPi7qsOyuxqrpaO1GSyxu0pZRayrKroWoVKSE0yNLldBW1pEwLUJuutAoIcJ99e_LdxPBnpjQ1g0-W-pyPwpwahBpQctCY0a__oeswxzGny1SlywpqIV6pO9NT40cXprzf1rQ5lbpCzRXfeh2_Q-Xb0eBtGMn5_P-P4OhJYGNIKZJrNtEPJj40HJptbc2b2jL95Tnq3A7UvbB_S8JHn4WN5g</recordid><startdate>20240511</startdate><enddate>20240511</enddate><creator>Gläser, Timothy</creator><creator>Böhringer, Daniel</creator><creator>Evers, Charlotte</creator><creator>Keye, Philip</creator><creator>Reinhard, Thomas</creator><creator>Lübke, Jan</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3946-5759</orcidid><orcidid>https://orcid.org/0000-0001-8307-5267</orcidid></search><sort><creationdate>20240511</creationdate><title>Clinical Results of the MINIject Implant for Suprachoroidal Drainage</title><author>Gläser, Timothy ; Böhringer, Daniel ; Evers, Charlotte ; Keye, Philip ; Reinhard, Thomas ; Lübke, Jan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c309t-646dc7355d69f24ef339b4779774d605b8e8229074f9235ebe8ab006ad4c80e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Automation</topic><topic>Care and treatment</topic><topic>Diagnosis</topic><topic>Eye</topic><topic>Eye surgery</topic><topic>Glaucoma</topic><topic>Patients</topic><topic>Regression analysis</topic><topic>Surgery</topic><topic>Survival analysis</topic><topic>Topical medication</topic><topic>Transplants & implants</topic><topic>Visual acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gläser, Timothy</creatorcontrib><creatorcontrib>Böhringer, Daniel</creatorcontrib><creatorcontrib>Evers, Charlotte</creatorcontrib><creatorcontrib>Keye, Philip</creatorcontrib><creatorcontrib>Reinhard, Thomas</creatorcontrib><creatorcontrib>Lübke, Jan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gläser, Timothy</au><au>Böhringer, Daniel</au><au>Evers, Charlotte</au><au>Keye, Philip</au><au>Reinhard, Thomas</au><au>Lübke, Jan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Results of the MINIject Implant for Suprachoroidal Drainage</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2024-05-11</date><risdate>2024</risdate><volume>13</volume><issue>10</issue><spage>2831</spage><pages>2831-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>This retrospective study evaluated the safety and efficacy of the new minimally invasive MINIject implant placed in the suprachoroidal space. The aim was to assess its impact on intraocular pressure (IOP) reduction and complication rate.
18 eyes from 18 patients with insufficiently controlled glaucoma received the implant using topical medications. Outcomes were changes in IOP, change in IOP medication, need for other glaucoma surgery, and rate of adverse events.
IOP reduced by 15% (
< 0.05) following MINIject implantation. IOP medication decreased from 3 to 1 agent (
< 0.05). Four patients (22%) required other glaucoma surgery while we did not observe any clinically relevant adverse event.
This retrospective study indicates that MINIject implants may be a safe and effective means of reducing IOP together with a reduction in IOP medications in most patients. Larger prospective studies with longer follow-ups are necessary to confirm our results, though.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38792373</pmid><doi>10.3390/jcm13102831</doi><orcidid>https://orcid.org/0000-0002-3946-5759</orcidid><orcidid>https://orcid.org/0000-0001-8307-5267</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Automation Care and treatment Diagnosis Eye Eye surgery Glaucoma Patients Regression analysis Surgery Survival analysis Topical medication Transplants & implants Visual acuity |
| title | Clinical Results of the MINIject Implant for Suprachoroidal Drainage |
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