Survival patterns and prognostic factors of gingivobuccal complex squamous cell cancer: A monocentric retrospective chart audit

•An audit of the oncological treatment and survival outcomes of a cohort of lower GBC cancers.•Treatment done at a single center in Odisha.•Large sample size.•Adequate long term follow-up data.•All patients treated by single operating surgeon.•Multivariate analysis for identifying significant progno...

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Veröffentlicht in:Oral oncology 2024-07, Vol.154, p.106857-106857, Article 106857
Hauptverfasser: Singh, Monika, Mishra, Niranjan, Ray, Satyashree, Bhusan Kar, Indu, Sharma, Gaurav
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Sprache:eng
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Zusammenfassung:•An audit of the oncological treatment and survival outcomes of a cohort of lower GBC cancers.•Treatment done at a single center in Odisha.•Large sample size.•Adequate long term follow-up data.•All patients treated by single operating surgeon.•Multivariate analysis for identifying significant prognostic factor influencing survival. To analyze the impact of clinico-pathological prognostic factors on survival in patients with GBC OSCC. To evaluate the association between various clino-pathological and treatment factors influencing the 3-year and 5-year Overall survival (OS), and Disease specific survival (DSS) in patients with lower GBC OSCC. An Institutional Ethical Committee (IEC) approved retrospective chart audit was performed. Biopsy proven squamous cell cancer of gingivobuccal complex (GBC OSCC) patients from 2010 to 2019 who were treated primarily with surgery with or without adjuvant therapy having complete clinicopathological and follow up data were included. Survival outcomes including 2-year, 3-year & 5-year OS, and DSS were calculated and analyzed. A multivariate analysis was performed to identify significant predictor for the survival outcomes. A p-value 
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2024.106857