Decreased thrombospondin-1 impairs endometrial stromal decidualization in unexplained recurrent spontaneous abortion

Abstract Inappropriate endometrial stromal decidualization has been implied as an important reason of many pregnancy-related complications, such as unexplained recurrent spontaneous abortion, preeclampsia, and intrauterine growth restriction. Here, we observed that thrombospondin-1, an adhesive glyc...

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Veröffentlicht in:	Biology of reproduction 2024-08, Vol.111 (2), p.448-462
Hauptverfasser:	Hu, Jianing, Qin, Chuanmei, Xu, Yichi, Liu, Xueqing, Wei, Xiaowei, Wu, Jiayi, Zhao, Xiaomiao, Chen, Cailian, Lin, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - genetics Abortion, Habitual - metabolism Adult Animals Decidua Decidua - metabolism Endometrium Endometrium - metabolism Endometrium - pathology Female Fetal resorption Fetuses Humans Kinases Male Mice Miscarriage Pre-eclampsia Pregnancy Pregnancy complications Prolactin Signal transduction Stromal Cells - metabolism Thrombospondin Thrombospondin 1 - genetics Thrombospondin 1 - metabolism
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