Supplementation with autologous adipose stem cell-derived mitochondria can be a safe and promising strategy for improving oocyte quality

Purpose In our previous study, we confirmed that the supplementation of vitrified-warmed murine oocytes with autologous adipose stem cell (ASC)-derived mitochondria during intracytoplasmic sperm injection enhances post-fertilization developmental competence in mice. To ensure the safety of this tech...

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Veröffentlicht in:	Journal of assisted reproduction and genetics 2024-08, Vol.41 (8), p.2065-2077
Hauptverfasser:	Kankanam Gamage, Sanath Udayanga, Hashimoto, Shu, Miyamoto, Yuki, Nakano, Tatsuya, Yamanaka, Masaya, Kitaji, Hideki, Takada, Yuki, Matsumoto, Hiroshi, Koike, Akiko, Satoh, Manabu, Ichishi, Masako, Watanabe, Masatoshi, Morimoto, Yoshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Activity patterns Adipose Tissue - cytology Animals Body temperature Comparative analysis Cryopreservation - methods Embryos Epigenetics Female Fertilization Gamete Biology Growth rate Gynecology Human Genetics Humans Male Medicine Medicine & Public Health Mice Mitochondria Mitochondria - metabolism Offspring Oocytes Oocytes - growth & development Reproductive Medicine Sperm Injections, Intracytoplasmic - methods Stem cells Stem Cells - cytology Stem Cells - metabolism Supplements
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