Maturation of Human iPSC‐Derived Cardiac Microfiber with Electrical Stimulation Device

Here an electrical stimulation system is described for maturing microfiber‐shaped cardiac tissue (cardiac microfibers, CMFs). The system enables stable culturing of CMFs with electrical stimulation by placing the tissue between electrodes. The electrical stimulation device provides an electric field...

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Veröffentlicht in:	Advanced healthcare materials 2024-10, Vol.13 (27), p.e2303477-n/a
Hauptverfasser:	Masuda, Akari, Kurashina, Yuta, Tani, Hidenori, Soma, Yusuke, Muramatsu, Jumpei, Itai, Shun, Tohyama, Shugo, Onoe, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	cardiac maturation Connexin 43 Coronary artery disease Electric fields electrical stimulation Electrical stimuli engineered heart tissues Gap junctions Gene expression Heart diseases hiPSC‐derived cardiomyocytes Maturation Microfibers microfiber‐shaped tissues Potassium channels (inwardly-rectifying) Stimulation
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