Race, substance use, and evaluation for heart transplantation: Insights from a large urban medical center
It is unknown whether racial disparities in access to heart transplantation (HT) are amplified when coupled with substance use. We examined patients evaluated for HT over 8 years at an urban transplant center. We evaluated substance use and race/ethnicity as independent and interactive predictors of...
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| Veröffentlicht in: | The Journal of heart and lung transplantation 2024-09, Vol.43 (9), p.1521-1524 |
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| container_title | The Journal of heart and lung transplantation |
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| creator | Chuzi, Sarah Cabrera, Elizabeth Ilonze, Onyedika Vela, Alyssa Pifer, Lindsay Wu, Tingqing Baldridge, Abigail S. Harap, Rebecca Youmans, Quentin Ghafourian, Kambiz Tibrewala, Anjan |
| description | It is unknown whether racial disparities in access to heart transplantation (HT) are amplified when coupled with substance use. We examined patients evaluated for HT over 8 years at an urban transplant center. We evaluated substance use and race/ethnicity as independent and interactive predictors of HT and left ventricular assist device (LVAD) implantation. Of 1,148 patients evaluated for HT, substance use was cited as an ineligibility factor in 151 (13%) patients, 16 (11%) of whom ultimately received HT. Significantly more non-Hispanic Black (NHB) patients were deemed ineligible due to substance use (n = 59, 19%) compared to other races/ethnicities (non-Hispanic white: n = 68, 12%; other race/ethnicity: n = 24, p = 0.002). No racial differences were observed in the likelihood of HT among patients initially excluded for substances, but more NHB patients ultimately received LVAD than the other racial groups. This study encourages greater awareness of the role of substance use and race in the HT evaluation. |
| doi_str_mv | 10.1016/j.healun.2024.05.011 |
| format | Article |
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We examined patients evaluated for HT over 8 years at an urban transplant center. We evaluated substance use and race/ethnicity as independent and interactive predictors of HT and left ventricular assist device (LVAD) implantation. Of 1,148 patients evaluated for HT, substance use was cited as an ineligibility factor in 151 (13%) patients, 16 (11%) of whom ultimately received HT. Significantly more non-Hispanic Black (NHB) patients were deemed ineligible due to substance use (n = 59, 19%) compared to other races/ethnicities (non-Hispanic white: n = 68, 12%; other race/ethnicity: n = 24, p = 0.002). No racial differences were observed in the likelihood of HT among patients initially excluded for substances, but more NHB patients ultimately received LVAD than the other racial groups. This study encourages greater awareness of the role of substance use and race in the HT evaluation.</description><identifier>ISSN: 1053-2498</identifier><identifier>ISSN: 1557-3117</identifier><identifier>EISSN: 1557-3117</identifier><identifier>DOI: 10.1016/j.healun.2024.05.011</identifier><identifier>PMID: 38763406</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Black or African American - statistics & numerical data ; disparities ; Female ; health equity ; Healthcare Disparities - ethnology ; Healthcare Disparities - statistics & numerical data ; Heart Failure - ethnology ; Heart Failure - surgery ; heart transplantation ; Heart Transplantation - statistics & numerical data ; Heart-Assist Devices ; Humans ; left ventricular assist device ; Male ; Middle Aged ; Racial Groups - statistics & numerical data ; Retrospective Studies ; substance use ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - ethnology ; White People - statistics & numerical data</subject><ispartof>The Journal of heart and lung transplantation, 2024-09, Vol.43 (9), p.1521-1524</ispartof><rights>2024 International Society for the Heart and Lung Transplantation</rights><rights>Copyright © 2024 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c241t-65247a28cf3ce700dd3072283249679b3fcb92a71e04023b3d13b2ef717b76143</cites><orcidid>0000-0002-5308-344X ; 0000-0003-2038-7786 ; 0000-0003-3174-5577 ; 0000-0001-5348-2742 ; 0000-0002-5180-2754 ; 0000-0002-3376-7748 ; 0000-0003-2816-6590 ; 0000-0001-5818-8091</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.healun.2024.05.011$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38763406$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chuzi, Sarah</creatorcontrib><creatorcontrib>Cabrera, Elizabeth</creatorcontrib><creatorcontrib>Ilonze, Onyedika</creatorcontrib><creatorcontrib>Vela, Alyssa</creatorcontrib><creatorcontrib>Pifer, Lindsay</creatorcontrib><creatorcontrib>Wu, Tingqing</creatorcontrib><creatorcontrib>Baldridge, Abigail S.</creatorcontrib><creatorcontrib>Harap, Rebecca</creatorcontrib><creatorcontrib>Youmans, Quentin</creatorcontrib><creatorcontrib>Ghafourian, Kambiz</creatorcontrib><creatorcontrib>Tibrewala, Anjan</creatorcontrib><title>Race, substance use, and evaluation for heart transplantation: Insights from a large urban medical center</title><title>The Journal of heart and lung transplantation</title><addtitle>J Heart Lung Transplant</addtitle><description>It is unknown whether racial disparities in access to heart transplantation (HT) are amplified when coupled with substance use. We examined patients evaluated for HT over 8 years at an urban transplant center. We evaluated substance use and race/ethnicity as independent and interactive predictors of HT and left ventricular assist device (LVAD) implantation. Of 1,148 patients evaluated for HT, substance use was cited as an ineligibility factor in 151 (13%) patients, 16 (11%) of whom ultimately received HT. Significantly more non-Hispanic Black (NHB) patients were deemed ineligible due to substance use (n = 59, 19%) compared to other races/ethnicities (non-Hispanic white: n = 68, 12%; other race/ethnicity: n = 24, p = 0.002). No racial differences were observed in the likelihood of HT among patients initially excluded for substances, but more NHB patients ultimately received LVAD than the other racial groups. 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Cabrera, Elizabeth ; Ilonze, Onyedika ; Vela, Alyssa ; Pifer, Lindsay ; Wu, Tingqing ; Baldridge, Abigail S. ; Harap, Rebecca ; Youmans, Quentin ; Ghafourian, Kambiz ; Tibrewala, Anjan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c241t-65247a28cf3ce700dd3072283249679b3fcb92a71e04023b3d13b2ef717b76143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Black or African American - statistics & numerical data</topic><topic>disparities</topic><topic>Female</topic><topic>health equity</topic><topic>Healthcare Disparities - ethnology</topic><topic>Healthcare Disparities - statistics & numerical data</topic><topic>Heart Failure - ethnology</topic><topic>Heart Failure - surgery</topic><topic>heart transplantation</topic><topic>Heart Transplantation - statistics & numerical data</topic><topic>Heart-Assist Devices</topic><topic>Humans</topic><topic>left ventricular assist device</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Racial Groups - statistics & numerical data</topic><topic>Retrospective Studies</topic><topic>substance use</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - ethnology</topic><topic>White People - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chuzi, Sarah</creatorcontrib><creatorcontrib>Cabrera, Elizabeth</creatorcontrib><creatorcontrib>Ilonze, Onyedika</creatorcontrib><creatorcontrib>Vela, Alyssa</creatorcontrib><creatorcontrib>Pifer, Lindsay</creatorcontrib><creatorcontrib>Wu, Tingqing</creatorcontrib><creatorcontrib>Baldridge, Abigail S.</creatorcontrib><creatorcontrib>Harap, Rebecca</creatorcontrib><creatorcontrib>Youmans, Quentin</creatorcontrib><creatorcontrib>Ghafourian, Kambiz</creatorcontrib><creatorcontrib>Tibrewala, Anjan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of heart and lung transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chuzi, Sarah</au><au>Cabrera, Elizabeth</au><au>Ilonze, Onyedika</au><au>Vela, Alyssa</au><au>Pifer, Lindsay</au><au>Wu, Tingqing</au><au>Baldridge, Abigail S.</au><au>Harap, Rebecca</au><au>Youmans, Quentin</au><au>Ghafourian, Kambiz</au><au>Tibrewala, Anjan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Race, substance use, and evaluation for heart transplantation: Insights from a large urban medical center</atitle><jtitle>The Journal of heart and lung transplantation</jtitle><addtitle>J Heart Lung Transplant</addtitle><date>2024-09</date><risdate>2024</risdate><volume>43</volume><issue>9</issue><spage>1521</spage><epage>1524</epage><pages>1521-1524</pages><issn>1053-2498</issn><issn>1557-3117</issn><eissn>1557-3117</eissn><abstract>It is unknown whether racial disparities in access to heart transplantation (HT) are amplified when coupled with substance use. We examined patients evaluated for HT over 8 years at an urban transplant center. We evaluated substance use and race/ethnicity as independent and interactive predictors of HT and left ventricular assist device (LVAD) implantation. Of 1,148 patients evaluated for HT, substance use was cited as an ineligibility factor in 151 (13%) patients, 16 (11%) of whom ultimately received HT. Significantly more non-Hispanic Black (NHB) patients were deemed ineligible due to substance use (n = 59, 19%) compared to other races/ethnicities (non-Hispanic white: n = 68, 12%; other race/ethnicity: n = 24, p = 0.002). No racial differences were observed in the likelihood of HT among patients initially excluded for substances, but more NHB patients ultimately received LVAD than the other racial groups. 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| fulltext | fulltext |
| identifier | ISSN: 1053-2498 |
| ispartof | The Journal of heart and lung transplantation, 2024-09, Vol.43 (9), p.1521-1524 |
| issn | 1053-2498 1557-3117 1557-3117 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult Aged Black or African American - statistics & numerical data disparities Female health equity Healthcare Disparities - ethnology Healthcare Disparities - statistics & numerical data Heart Failure - ethnology Heart Failure - surgery heart transplantation Heart Transplantation - statistics & numerical data Heart-Assist Devices Humans left ventricular assist device Male Middle Aged Racial Groups - statistics & numerical data Retrospective Studies substance use Substance-Related Disorders - epidemiology Substance-Related Disorders - ethnology White People - statistics & numerical data |
| title | Race, substance use, and evaluation for heart transplantation: Insights from a large urban medical center |
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