Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics

Gastrulation is a critical stage in embryonic development during which the germ layers are established. Advances in sequencing technologies led to the identification of gene regulatory programs that control the emergence of the germ layers and their derivatives. However, proteome-based studies of ea...

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Veröffentlicht in:	Cell stem cell 2024-07, Vol.31 (7), p.1072-1090.e8
Hauptverfasser:	Stelloo, Suzan, Alejo-Vinogradova, Maria Teresa, van Gelder, Charlotte A.G.H., Zijlmans, Dick W., van Oostrom, Marek J., Valverde, Juan Manuel, Lamers, Lieke A., Rus, Teja, Sobrevals Alcaraz, Paula, Schäfers, Tilman, Furlan, Cristina, Jansen, Pascal W.T.C., Baltissen, Marijke P.A., Sonnen, Katharina F., Burgering, Boudewijn, Altelaar, Maarten A.F.M., Vos, Harmjan R., Vermeulen, Michiel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Lineage developmental biology dTAG system Embryonic Development - genetics enhancers Gastrula - metabolism Gastrulation gastruloids Gene Expression Regulation, Developmental germ layers Humans interaction proteomics Mice Proteomics Single-Cell Analysis somitoids transcription factors ZEB2
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