Biomass-derived carbon dots as significant biological tools in the medicinal field: A review

Early disease detection is crucial since it raises the likelihood of treatment and considerably lowers the cost of therapy. Therefore, the improvement of human life and health depends on the development of quick, efficient, and credible biosensing methods. For improving the quality of biosensors, distinct nanostructures have been investigated; among these, carbon dots have gained much interest because of their great performance. Carbon dots, the essential component of fluorescence nanoparticles, having outstanding chemical characteristics, superb biocompatibility, chemical inertness, low toxicity and potential optical characteristics have attracted the researchers from every corner of the globe. Several carbon dots applications have been thoroughly investigated in recent decade, from optoelectronics to biomedical investigations. This review study primarily emphasizes the recent advancements in the field of biomass-derived carbon dots-based drug delivery, gene delivery and bioimaging, and highlights achievements in two major areas: in vivo applications that involve carbon dots absorption in zebrafish and mice, tumour therapeutics, and imaging-guided drug delivery. Additionally, the possible advantages, difficulties, and future possibilities of using carbon dots for biological applications are also explored. [Display omitted] •Early disease detection is crucial since it raises the likelihood of treatment.•Carbon dots are excellent nano-biomaterials for various biomedical applications.•We have summarized biomedical applications using biomass-derived carbon dots.