Ionic reverberation modulates the cellular fate of CD8+tissue resident memory T cells (TRMs) in patients with renal cell carcinoma: A novel mechanism

In metastatic renal cell carcinoma (mRCC), existing treatments including checkpoint inhibitors are failed to cure and/or prevent recurrence of the disease. Therefore, in-depth understanding of tumor tissue resident memory T cells (TRMs) dysfunction are necessitated to enrich efficacy of immunotherap...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2024-07, Vol.264, p.110256, Article 110256
Hauptverfasser:	Singh, Ashu, Choudhury, Saumitra Dey, Singh, Prabhjot, Singh, Vishwendra Vikram, Singh, Som Nath, Sharma, Alpana
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ca2 Carcinoma, Renal Cell - immunology CD8-Positive T-Lymphocytes - drug effects CD8-Positive T-Lymphocytes - immunology Female Humans Immunologic Memory Ion Channels Kidney Neoplasms - immunology Male Memory T Cells - immunology Middle Aged mRCC Na2 TME TRMs Zn2
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