Concurrent inflammation-related brain reorganization in multiple sclerosis and depression

•Multiple sclerosis and major depression share morphologic network alterations.•The contrast between the gray and white matters may be a neuroinflammation marker.•Network alterations may underlie symptom severity and depression comorbidity in MS. Neuroinflammation affects brain tissue integrity in m...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2024-07, Vol.119, p.978-988
Hauptverfasser:	Molina Galindo, Lara S., Gonzalez-Escamilla, Gabriel, Fleischer, Vinzenz, Grotegerd, Dominik, Meinert, Susanne, Ciolac, Dumitru, Person, Maren, Stein, Frederike, Brosch, Katharina, Nenadić, Igor, Alexander, Nina, Kircher, Tilo, Hahn, Tim, Winter, Yaroslav, Othman, Ahmed E., Bittner, Stefan, Zipp, Frauke, Dannlowski, Udo, Groppa, Sergiu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - diagnostic imaging Brain - pathology Cortical morphometric covariance Cortical morphometry Depression - physiopathology Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - physiopathology Female Gray Matter - diagnostic imaging Gray Matter - pathology Gray-to-white matter junction Humans Inflammation Magnetic Resonance Imaging - methods Major depressive disorder Male Middle Aged Multiple sclerosis Multiple Sclerosis - complications Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - pathology Multiple Sclerosis - physiopathology Multiple Sclerosis - psychology Network reorganization Neuroinflammatory Diseases - diagnostic imaging White Matter - diagnostic imaging White Matter - pathology
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